General News | Specific countries | Industry News | Infectious Diseases | Resource Library | Journals
Collaborating Site: CSTM

General

• ISBT: 33rd Regional ISBT Congress in Gothenburg, Sweden (17-21June 2023)
• In Memoriam: Amoz Chernoff, MD (29 Mar. 2023)
• Hyporesponse to anemia drugs leads to higher rate of transfusions (17 Apr. 2023) | Related:
  • Ferro C, Benjumea D, Dieguez G, et al. Blood transfusion and transplant rates among Medicare patients with dialysis-dependent CKD and hyporesponse to ESAs. Presented at: NKF 2023 Spring Clinical Meetings, April 11-15, Austin, Texas. Poster 180.
• Leaps in artificial blood research aim to improve product safety, efficacy (17 Apr. 2023) | Related:
  • Greenfield A, Lamb DR, Gu X, et al. Biophysical analysis and preclinical pharmacokinetics-pharmacodynamics of tangential flow filtration fractionated polymerized human hemoglobin as a red blood cell substitute. Biomacromolecules. 2023 Apr 10;24(4):1855-70. Epub 2023 Mar 6.
• Red blood cell transfusions in patients with CKD and anemia (17 Apr. 2023) | Related:
  • Hunnicutt J, Ma L, Mu G, et al. Red blood cell (RBC) transfusion use varies by baseline hemoglobin (Hb) and is associated with post-transfusion hyperkalemia and hospitalization within 30 days in US patients with stage 3­5 CKD and anemia. Poster #182. Abstract of a poster presented at the National Kidney Foundation Spring Clinical Meetings 2023; April 11-15, 2023; Austin, Texas.
• Religious limitations likely not to preclude successful TTP therapy (16 Apr. 2023) | Related:
  • Tran MH. Therapeutic modalities in thrombotic thrombocytopenic purpura management among Jehovah's Witness patients: A review of reported cases. Transfus Apher Sci. 2023 Mar 21:103706. Epub ahead of print. (Free full text) | PubMed abstract
• Sex of red blood cell donor has no significant impact on transfusion recipient mortality (13 Apr. 2023) | Related:
  • Chassé M, Fergusson DA, Tinmouth A, et al. Effect of donor sex on recipient mortality in transfusion. N Engl J Med. 2023 Apr 13;388(15):1386-95.
• Marburg has health officials worried, but a vaccine may be on the horizon (13 Apr. 2023) | Related:
  • Hamer MJ, Houser KV, Hofstetter AR, et al; RV 507 Study Team. Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial. Lancet. 2023 Jan 28;401(10373):294-302.
• Despite access barriers, physicians prefer CAR-T for treatment of advanced B-cell lymphoma (13 Apr. 2023)
• Dried blood test may detect HIV, hepatitis B and C (12 Apr. 2023) | Related:
  • HIV, hepatitis B and hepatitis C can be detected from a single drop of blood, Danish study shows (12 Apr. 2023) | Press release from European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen, 15-18 April)
• Takeda Pharmaceuticals' ixazomib shows PFS benefit across age and frailty subgroups in multiple myeloma (12 Apr. 2023) | Related:
  • Bringhen S, Pour L, Benjamin R, et al. Ixazomib versus placebo as post-induction maintenance therapy in newly diagnosed multiple myeloma patients: an analysis by age and frailty status of the TOURMALINE-MM4 study. Clin Lymphoma Myeloma Leuk. Published online March 28, 2023. (Open access)
• Many patients with hemophilia experience functional declines over time (11 Apr. 2023) | Related:
  • Blokzijl J, Pisters MF, Veenhof C, et al. Functional decline in persons with haemophilia and factors associated with deterioration. Haemophilia. 2023 Mar 28. Epub ahead of print. (Open access) | PubMed abstract
• Study finds no evidence for common blood microbiome (11 Apr. 2023) | Related:
  • Tan CCS, Ko KKK, Chen H, et al; SG10K_Health Consortium; Chia M, Nagarajan N. No evidence for a common blood microbiome based on a population study of 9,770 healthy humans. Nat Microbiol. 2023 Mar 30. Epub ahead of print. (Open access) | PubMed abstract
• New nuclear medicine therapy cures human non-hodgkin lymphoma in preclinical model (11 Apr. 2023) | Related:
  • Shim K, Longtine MS, Abou DS, et al. Cure of disseminated humanl lymphoma with [¹⁷⁷Lu]Lu-ofatumumab in a preclinical model. J Nucl Med. 2023 Apr;64(4):542-8. Epub 2022 Nov 10. (Free full text) | PubMed abstract
• Review quantifies incidence of HIV, Hep C in persons who inject drugs (10 Apr. 2023) | Related:
  • Artenie A, Stone J, Fraser H, et al.; HIV and HCV Incidence Review Collaborative Group. Incidence of HIV and hepatitis C virus among people who inject drugs, and associations with age and sex or gender: a global systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2023 Mar 27:S2468-1253(23)00018-3. Epub ahead of print. (Open access) | PubMed abstract
• WHO warns climate change causing surge in mosquito-borne diseases (10 Apr. 2023)
• The dream of wiping out polio might need a rethink (10 Apr. 2023)
• Adding Roxane Laboratories' metronomic cyclophosphamide to Takeda Pharmaceuticals' ixazomib, Roxane Laboratories' cyclophosphamide, and dexamethasone not recommended for multiple myeloma (10 Apr. 2023) | Related:
  • Pelcovits A, Barth P, Reagan JL, et al. Ixazomib, oral metronomic cyclophosphamide, and dexamethasone for first-line treatment of multiple myeloma: A Phase II Brown University Oncology Group Study. Oncologist. 2023 Mar 21:oyad017. Epub ahead of print. (Free full text) | PubMed abstract
• Many childhood cancer survivors report late effects more than 15 years after diagnosis (10 Apr. 2023) | Related:
  • Signorelli C, Wakefield CE, McLoone JK, et al.; ANZCHOG Survivorship Study Group. Childhood cancer survivors' reported late effects, motivations for seeking survivorship care, and patterns of attendance. Oncologist. 2023 Mar 21:oyad004. Epub ahead of print. (Free full text) | PubMed abstract
• Risks identified for venous thromboembolism in acute hematogenous musculoskeletal infections in children (10 Apr. 2023) | Related:
  • Purtell SR, Thornhill D, Loi M, et al. Risk factors for venous thromboembolic events in children with acute musculoskeletal infections. J Pediatr Orthop. 2023 Mar 16. Epub ahead of print.
• Cancer and heart disease vaccines ‘ready by end of the decade’ (8 Apr. 2023)
• Study: Cognitive impairment in patients with HIV not exacerbated by COVID-19 in vaccinated individuals (6 Apr. 2023)
• Are hypertension and blood pressure change in early adulthood associated with late-life brain health, and is there variation by sex? (6 Apr. 2023) | Related:
  • George KM, Maillard P, Gilsanz P, et al. Association of early adulthood hypertension and blood pressure change with late-life neuroimaging biomarkers. JAMA Netw Open. 2023 Apr 3;6(4):e236431. (Free full text) | PubMed abstract
• IPSS-M shows strong predictive power in myelodysplastic syndrome (6 Apr. 2023) | Related:
  • Sauta E, Robin M, Bersanelli M, et al. Real-world validation of molecular international prognostic scoring system for myelodysplastic syndromes. J Clin Oncol. 2023 Mar 17:JCO2201784. Epub ahead of print. (Free full text) | PubMed abstract
• The impact of perinatal low-calorie sweetener exposure on the development of neural systems involved in metabolic regulation (6 Apr. 2023) | Related:
  • Park S, Belfoul AM, Rastelli M, et al. Maternal low-calorie sweeteners consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway. JCI Insight. 2023 Apr 4:e156397. Epub ahead of print. (Free full text) | PubMed abstract
• Prediction of major bleeding by machine learning shows promise in patients taking anticoagulation for VTE (6 Apr. 2023) | Related:
  • Mora D, Mateo J, Nieto JA, etal.; and the Registro Informatizado de Enfermedad TromboEmbólica (RIETE) Investigators. Machine learning to predict major bleeding during anticoagulation for venous thromboembolism: possibilities and limitations. Br J Haematol. 2023 Mar 21. Epub ahead of print. (Open access) | PubMed abstract
• Tranexamic acid may reduce blood loss, transfusion rates after hemiarthroplasty, THA (6 Apr. 2023)
• Shape-shifting antibiotics to combat drug-resistant bacteria (5 Apr. 2023) | Related:
  • Ottonello A, Wyllie JA, Yahiaoui O, et al. Shapeshifting bullvalene-linked vancomycin dimers as effective antibiotics against multidrug-resistant gram-positive bacteria. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2208737120. Epub 2023 Apr 3.
• CAR T cells improve quality of life for majority of recipients (4 Apr. 2023) | Related:
  • Johnson PCC, Dhawale TM, Newcomb RA, et al. Longitudinal patient-reported outcomes in patients receiving chimeric antigen receptor T-cell therapy. Blood Adv. 2023 Mar 30:bloodadvances.2022009117. Epub ahead of print.
• In pediatric patients, increased platelet transfusion linked to higher risk of infection, thrombosis and mortality (3 Apr. 2023) | Related:
  • Lang EA, An A, Finn S, et al. Epidemiology of platelet transfusions in hospitalized children: A pediatric hospital information system database study. Hosp Pediatr. 2023 Apr 1;13(4):283-92. (Free full text) | PubMed abstract
• Study proposes a roadmap to understand the extent of regeneration in the human brain (3 Apr. 2023) | Related:
  • Tosoni G, Ayyildiz D, Bryois J, et al. Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: Reconciling controversy or fueling the debate? Neuron. 2023 Mar 27:S0896-6273(23)00206-4. Epub ahead of print. (Open access) | PubMed abstract
• High, low hemoglobin levels without anemia predict mortality risk after CABG (3 Apr. 2023) | Related:
  • Khalaji A, Ajam A, Sheikhy A, et al. Mortality across the spectrum of hemoglobin level in patients undergoing surgical coronary revascularization. Clin Cardiol. 2023 Mar 23. Epub ahead of print. (Open access) | PubMed abstract
• Pembrolizumab plus ICE deemed effective in relapsed/refractory hodgkin lymphoma (3 Apr. 2023) | Related:
  • Bryan LJ, Casulo C, Allen PB, et al. Pembrolizumab added to ifosfamide, carboplatin, and etoposide chemotherapy for relapsed or refractory classic hodgkin lymphoma: A multi-institutional phase 2 investigator-initiated nonrandomized clinical trial. JAMA Oncol. 2023 Mar 16:e227975. Epub ahead of print.
• British Society for Haematology guideline for anticoagulant management of pregnant individuals with mechanical heart valves (1 Apr. 2023)
• There's a second outbreak of Marburg virus in Africa. Climate change could be a factor (31 Mar. 2023)
• Hepatitis C diagnosis increasing among pregnant women (31 Mar. 2023) | Related:
  • Arditi B, Emont J, Friedman AM, et al. Deliveries among patients with maternal hepatitis C virus infection in the United States, 2000-2019. Obstet Gynecol. 2023 Apr 1;141(4):828-36. Epub 2023 Mar 9.
• Monthly injections might lower bleeding in people with hemophilia (31 Mar. 2023) | Related:
  • Young G, Srivastava A, Kavakli K, et al. Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with inhibitors (ATLAS-INH): a multicentre, open-label, randomised phase 3 trial. Lancet. 2023 Mar 29:S0140-6736(23)00284-2. Epub ahead of print.
• What is the association between the number of days taking a sufficient number of steps throughout the week and mortality among US adults? (31 Mar. 2023) | Related:
  • Inoue K, Tsugawa Y, Mayeda ER, Ritz B. Association of daily step patterns with mortality in US adults. JAMA Netw Open. 2023 Mar 1;6(3):e235174. (Free full text) | PubMed abstract
• Bristol Myers Squibb's liso-cel receives European approval recommendation for relapsed/refractory LBCL (31 Mar. 2023)
• ‘Best match’ transfusions an option for CAD children, despite concerns (31 Mar. 2023) | Related:
  • Sekhar Das S, Chaudhuri K, Mukherjee S. Clinical and immunohematological characterization of autoimmune hemolytic anemia in children. Transfus Apher Sci. 2023 Mar 15:103703. Epub ahead of print. (Free full text) | PubMed abstract
• 'We have arrived in the post-antibiotic era': WHO warns of too few new drugs for deadly superbugs (29 Mar. 2023)
• Translation of “jumping genes” creates cancer therapy targets (29 Mar. 2023) | Related:
  • Shah NM, Jang HJ, Liang Y, et al. Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements. Nat Genet. 2023 Mar 27. Epub ahead of print. (Free full text) | PubMed abstract
• Elevated umbilical cord insulin concentration tied to high blood pressure in offspring (28 Mar. 2023) | Related:
  • Wang G, Buckley JP, Bartell TR, et al. Cord Blood insulin concentration and hypertension among children and adolescents enrolled in a US racially diverse birth cohort. Hypertension. 2023 Mar 13. Epub ahead of print.
• Finger-prick test developed for ‘trich’ a common, undiagnosed STI (27 Mar. 2023) | Related:
  • Alderete JF, Chan H. Point-of-care diagnostic for Trichomonas vaginalis, the most prevalent, non-viral sexually transmitted infection. Pathogens. 2023 Jan 3;12(1):77. (Open access) | PubMed abstract
• Women’s College Hospital researcher discovers new hereditary breast cancer gene (27 Mar. 2023) | Related:
  • Cybulski C, Zamani N, Kluzniak W, et al. Variants in ATRIP are associated with breast cancer susceptibility in the Polish population and UK Biobank. Am J Hum Genet. 2023 Apr 6;110(4):648-62. Epub 2023 Mar 27.
• Functional thymus organoids successfully grown from human stem cells (27 Mar. 2023) | Related:
  • Ramos SA, Armitage LH, Morton JJ, et al. Generation of functional thymic organoids from human pluripotent stem cells. Stem Cell Reports. 2023 Mar 14:S2213-6711(23)00060-7. Epub ahead of print. (Open access) | PubMed abstract
• Use of pain, depression, anxiety meds higher among patients with hemophilia (26 Mar. 2023) | Related:
  • Steen Carlsson K, Winding B, Astermark J, et al. High use of pain, depression, and anxiety drugs in hemophilia: more than 3000 people with hemophilia in an 11-year Nordic registry study. Res Pract Thromb Haemost. 2023 Jan 31;7(2):100061. (Open access) | PubMed abstract
• WHO report highlights impact of COVID-19 pandemic on non-communicable diseases (24 Mar. 2023) | Related:
  • Access to NCD medicines: emergent issues during the COVID-19 pandemic and key structural factors (22 Mar. 2023)
• ‘Smart' bandages monitor wounds and provide targeted treatment (24 Mar. 2023) | Related:
  • Shirzaei Sani E, Xu C, et al. A stretchable wireless wearable bioelectronic system for multiplexed monitoring and combination treatment of infected chronic wounds. Sci Adv. 2023 Mar 24;9(12):eadf7388. Epub 2023 Mar 24. (Free full text) | PubMed abstract
• Declining hemoglobin linked with growth impairment among children with CKD (24 Mar. 2023) | Related:
  • Akchurin O, Molino AR, Schneider MF, et al. Longitudinal relationship between anemia and statural growth impairment in children and adolescents with nonglomerular CKD: Findings From the Chronic Kidney Disease in Children (CKiD) Study. Am J Kidney Dis. 2023 Apr;81(4):457-465.e1. Epub 2022 Dec 5.
• Higher hemoglobin levels tied to lower end-organ damage risk (23 Mar. 2023) | Related:
  • Ershler WB, De Castro LM, Pakbaz Z, et al. Hemoglobin and end-organ damage in individuals with sickle cell disease. Curr Ther Res Clin Exp. 2023 Feb 23;98:100696. (Free full text) | PubMed abstract
• Most HIV mortality now due to non-AIDS-related comorbidities (22 Mar. 2023) | Related:
  • WHO: Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy
• NIH study reveals shared genetic markers underlying substance use disorders (22 Mar. 2023) | Related:
  • Hatoum AS, Colbert SMC, Johnson EC, et al. Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders. Nat. Mental Health 1, 210­223 (2023). Epub 22 Mar. 2023. (Free full text)
• Minimal residual disease negativity predicts time to next treatment in multiple myeloma (22 Mar. 2023) | Related:
  • Fonseca R, Arribas M, Wiedmeier-Nutor JE, et al. Integrated analysis of next generation sequencing minimal residual disease (MRD) and PET scan in transplant eligible myeloma patients. Blood Cancer J. 2023 Mar 6;13(1):32. (open access) | PubMed abstract
• Risk of second malignancies not elevated among older MPN patients treated with hydroxyurea (21 Mar. 2023) | Related:
  • Wang R, Shallis RM, Stempel JM, et al. Second malignancies among older patients with classical myeloproliferative neoplasms treated with hydroxyurea. Blood Adv. 2023 Mar 14;7(5):734-43. (Free full text) | PubMed abstract
• New treatment using nanoparticles can repair lymphatic vessel pumping (20 Mar. 2023) | Related:
  • Sestito LF, To KHT, Cribb MT, et al. Lymphatic-draining nanoparticles deliver Bay K8644 payload to lymphatic vessels and enhance their pumping function. Sci Adv. 2023 Feb 24;9(8):eabq0435. Epub 2023 Feb 24. (Free full text) | PubMed abstract
• Machine learning applications for the diagnosis, treatment and prognosis of cancer (19 Mar. 2023) | Related:
  • Swanson K, Wu E, Zhang A, et al. From patterns to patients: Advances in clinical machine learning for cancer diagnosis, prognosis, and treatment. Cell. 2023 Mar 7:S0092-8674(23)00094-6. Epub ahead of print.
• Colorectal cancer and E. coli: new insights (16 Mar. 2023) | Related:
  • Oliero M, Hajjar R, Cuisiniere T, et al. Prevalence of pks + bacteria and enterotoxigenic Bacteroides fragilis in patients with colorectal cancer. Gut Pathog. 2022 Dec 28;14(1):51. (Open access) | PubMed abstract
• Improving patient care in complex times (15 Mar. 2023)
• Bioluminescent proteins could help diagnose viral diseases (15 Mar. 2023) | Related:
  • van der Veer HJ, van Aalen EA, Michielsen CMS, et al. Glow-in-the-dark infectious disease diagnostics using CRISPR-Cas9-Based Split luciferase complementation. ACS Cent Sci.2023. Epub 15 Mar. 2023. (Free full text)
• How should patients with acute heart failure be monitored? This tool can help. (7 Mar. 2023) | Related:
  • Lee DS, Straus SE, Farkouh ME, et al.; COACH Trial Investigators. Trial of an intervention to improve acute heart failure outcomes. N Engl J Med. 2023 Jan 5;388(1):22-32. Epub 2022 Nov 5.

Canada

• McMaster scientist Lori Burrows wins prestigious award for superbug research (27 Mar. 2023)
• B.C. rebuffs Canadian Blood Services, will not allow private company to collect blood plasma (16 Apr. 2023)
• Manitoba hospitals achieve province-wide using Blood Wisely Hospital Designation Status (14 Apr. 2023)
• Extended-release formulation of Taro Pharmaceutical's Ferriprox now approved in Canada (4 Apr. 2023)
• New free celiac blood tests could benefit 128,000 Ontarians and save $1 billion (30 Mar. 2023)
• 'Stars all lined up perfectly': Edmonton wildlife rescue performs rare porcupine blood transfusion (28 Mar. 2023)
• CBS: Professional education events (8 in Apr. 2023)
• CSTM 2023 Conference, Montréal (25-28 May, 2023)
• CSMLS LabCon 2023 (Whistler, BC May 26-28, 2023)
• International symposium on individualized behavioural deferral criteria: 20 Apr. 2023 (Héma-Québec & Canadian Blood Services webinar)
• CBS/ORBCoN Technical Dry Workshop: Fear and Loathing in the blood bank (26 Apr. 2023)
• ORBCoN and CBS 18th Annual Transfusion Medicine Educational Web Conference Symposium (27 Apr. 2023)

ORBCoN resources:

• The OrbCon Report April 2023 | In this issue:
  • ORBCoN’s eLearning Resources- Helping to Meet Accreditation Requirements
  • Bloody Easy Lite Learning Modules 1 & 2 Spring 2023 The 18th Annual Transfusion Medicine Education Symposium
  • Newsboard
    • MHP Implementation Survey
  • Upcoming Events
    • CBS/ORBCoN Technical Dry Workshop Register: 18th Annual Transfusion Medicine Webconference
    • UofT TM Rounds

Afghanistan

• Lack of aid, surging patients dry up Afghanistan’s blood bank (8 Apr. 2023)

Australia

• Blood for a bandage: designer Camilla Franks’ new mission (11 Apr. 2023)
• 12 sweet reasons to donate blood this Easter (4 Apr. 2023)
• Vets in urgent need of four-legged donors to boost pet blood supplies (1 Apr. 2023)
• Pioneering “poo transplant” trial gives hope to severely ill cancer patients (28 Mar. 2023)
• Desperate plea for blood donations from pets amid national shortage (28 Mar. 2023)

Haiti

• Haiti in dire need of “safe blood” (6 Apr. 2023)

India

• Mumbai: Call for blood donation ahead of summer vacation (18 Apr. 2023)
• Priyanka’s death due to negligence, says autopsy; Chhola doc booked (17 Apr. 2023)
• Blood banks to inform SBTC of hepatitis positive patients (8 Apr. 2023)
• Make Telangana thalassemia-free (6 Apr. 2023)
• NITI Aayog, TBCT’s pilot assessment of blood transfusion infra in UP reveals improved functioning by 37% through PPP model (4 Apr. 2023)
• HIV transmission through blood transfusion now at less than 1% as compared to 15% earlier: NACO (31 Mar. 2023)
• DBT institute develops novel bags to increase shelf life of blood (27 Mar. 2023)
• Robust technology, cold chain key to efficient blood management and safety (27 Mar. 2023)

Ireland

• Blood donation clinics returning to Limerick community for the first time since Covid (12 Apr. 2023)
• Low blood stocks bring new Easter donation clinics to Limerick (6 Apr. 2023)

Mexico

• Donating blood has gone from being an altruistic task to a task (25 Mar. 2023)

Nepal

• IFRC, NDRRMA sign deal for reducing disaster risks (14 Apr. 2023)

Netherlands

• The Netherlands will introduce individual donor assessment in 2024 (20 Mar. 2023)

Nigeria

• No blackout, negative blood transfusion in University College Hospital (UCH) - management (21 Mar. 2023)
• ‘Epileptic power supply worsens blood transfusion In UCH’ - Group alleges (20 Mar. 2023) | The UCH at nights is now like ghost community with patients lacking quality medical support in the face of power outages.

Pakistan

• Officials scamper to screen villagers as local blood donor dies of HIV (18 Apr. 2023)

Spain

• Helicopter 061: saving lives in mid-air (14 Apr. 2023)

Sudan

• Death toll nears 200 as Sudan spins out of control (18 Apr. 2023) | The World Health Organisation had already warned that some of Khartoum’s nine hospitals tending to wounded civilians “have run out of blood, transfusion equipment, intravenous fluids and other vital supplies”.

Uganda

• Health experts seek law to regulate blood transfusion services (31 Mar. 2023)
• Minister of Health Aceng: Lack of policy hindering blood transfusion services (31 Mar. 2023)

UK

• SHOT celebrates its Silver Jubilee in 2022
• Mum tells of heartache after losing baby to twin transfusion syndrome (17 Apr. 2023)

Infected Blood Inquiry - News**

• I received £100k as compensation for the infected blood scandal. Do I have to pay tax on the interest? (18 Apr. 2023)
• Contaminated blood scandal victims 'finally being recognised' (6 Apr. 2023)
• Contaminated blood inquiry: Dad wants family's pain recognised (6 Apr. 2023)
• Government told to ‘do what’s right’ and extend infected blood payouts (5 Apr. 2023)
• UK’s infected blood inquiry calls for extension of compensation (5 Apr. 2023)
• Infected blood inquiry: 'Compensation should recognise wider families (4 Apr. 2023)

Ukraine

• The flying hospital bringing Ukraine's wounded west (29 Mar. 2023)
• Civilians in Crimean hospitals experience blood and medicine shortages due to Russian military being treated there (19 Mar. 2023)

USA^

• Houston Army veteran needs a life-saving stem cell donor | How you can help (15 Apr. 2023)
• The Biden administration will hang on to some Covid pandemic emergency powers (14 Apr. 2023)
• States confront medical debt that’s bankrupting millions (13 Apr. 2023)
• Chronic pain affects 21% of Americans, CDC reports (13 Apr. 2023) | Related:
  • Rikard SM, Strahan AE, Schmit KM, et al. Chronic pain among adults - United States, 2019-2021. MMWR Morb Mortal Wkly Rep. 2023 Apr 14;72(15):379-85. (Free full text) | PubMed abstract
• Biden extending Affordable Care Act and Medicaid coverage to DACA recipients (13 Apr. 2023)
• FDA grants orphan drug designation to Oncolyze's OM-301 in multiple myeloma (13 Apr. 2023)
• More than half of gay, bisexual men would donate blood if eligible, HRC survey finds (12 Apr. 2023) | Related:
  • LGBTQ+ community attitudes towards current and proposed FDA blood donation guidelines (Human Rights Campaign. Updated: 17 Mar. 2023)
• CMS seeks feedback on palliative blood transfusion in proposed FY 2024 hospice rule (12 Apr. 2023)
• Personalized outreach impacts ACA enrollment among low income households (12 Apr. 2023) | Related:
  • Feher A, Menashe I, Miller J, Wolf E. Personalized letters and emails increased marketplace enrollment among households eligible for zero-premium plans. Health Aff (Millwood). 2023 Apr;42(4):585-93.
• One pint to save three lives: Hospitals’ blood supply continues to recovery after the 2022 crisis (12 Apr. 2023)
• FDA outlines risk-based approach to monitoring clinical trials (11 Apr. 2023)
• STDs continue to climb in the U.S. (11 Apr. 2023) | Related:
  • ASTHO and NCSD issue joint statement on concerning rise in syphilis cases across U.S. (11 Apr. 2023)
• CMS proposes 2.8% rate increase for inpatient payments in 2024 (11 Apr. 2023) | Related:
  • CMS proposes 2.8% hospital payment bump for 2024; lobbies decry rise as ‘woefully inadequate’ (11 Apr. 2023)
• FDA puts Molecular Templates' multiple myeloma trial on partial hold—500 days after adverse event (10 Apr. 2023)
• HHS cuts 7 drugs from Medicare Part B rebates list (10 Apr. 2023)
• 'Finding True America': I 'donate' plasma 104 times a year to make a living (8 Apr. 2023)
• COVID-19 remained deadlier than flu this past season (8 Mar. 2023) | Related:
  • Xie Y, Choi T, Al-Aly Z. Risk of death in patients hospitalized for COVID-19 vs seasonal influenza in fall-winter 2022-2023. JAMA. 2023 Apr 6:e235348. Epub ahead of print. (Free full text)
• Bronx Masonic District partners with New York Blood Center for 80th blood drive (8 Apr. 2023)
• Adventhealth Gordon to host blood drive (8 Apr. 2023)
• Michigan AG urges FDA to change "discriminatory" blood donor policy (7 Apr. 2023)
• COVID-19 hospitalizations up in 16 states 1 month out from end of PHE (6 Apr. 2023)
• Where is the White House’s new pandemic response office? (6 Apr. 2023)
• Two major stem cell research projects supported with more than $2.6 million in funding (6 Apr. 2023)
• San Antonio City Council participates in the SA Challenge for blood donations (6 Apr. 2023)
• Industry news: FDA fast tracks Caribou Biosciences' CB-011 for relapsed/refractory multiple myeloma (6 Apr. 2023)
• Medicare Advantage final rule addresses prior authorization, health equity (5 Apr. 2023) | Related:
  • CMS to phase in Medicare Advantage risk adjustment changes, bumping payments by 3% (31 Mar. 2023)
• Biden says U.S. must address ‘potential risks’ of AI (4 Apr. 2023)
• FDA will let some adults get a second boost of the bivalent COVID-19 shot (4 Apr. 2023)
• FDA accepts Glenmark Pharmaceuticals' IND for HPK1 inhibitor in advanced solid tumors and lymphomas (4 Apr. 2023)
• National Cancer Plan outlines eight goals, strategies to achieve Biden’s Moonshot vision (3 Apr. 2023)
• FDA inspection finds sterilization issues at recalled eye drop manufacturer’s facility (3 Apr. 2023) | Related:
  • Two additional deaths linked to bacteria in recalled eye drops, CDC says (22 Mar. 2023) | Related:
  • Morelli MK, Kloosterboer A, Omar AF. Pseudomonas aeruginosa corneal ulcer associated with artificial tears eye drops. JAMA Ophthalmol. 2023 Mar 22. Epub ahead of print. (Free abstract)
• Wisconsin fungal infection sickened 4 people, 5 dogs (3 Apr. 2023) | Related:
  • Segaloff HE, Wu K, Shaw S, et al. Notes from the field: Cluster of blastomycosis among neighborhood residents - St. Croix County, Wisconsin, 2022. MMWR Morb Mortal Wkly Rep. 2023 Mar 31;72(13):348-9. (Free full text)
• CDC to warn some travelers to watch for Marburg virus symptoms as it investigates outbreaks in Africa (31 Mar. 2023)
• Columbia Healthcare Analytics: Recent study indicates hospitals excessively transfuse blood (31 Mar. 2023) | Related:
  • Jadwin DF, Fenderson PG, Friedman MT, et al. Determination of unnecessary blood transfusion by comprehensive 15-hospital record review. Jt Comm J Qual Patient Saf. 2023 Jan;49(1):42-52. Epub 2022 Nov 8. (Open access) | PubMed abstract
• Federal judge says insurers no longer have to provide some preventive care services, including cancer and heart screenings, at no cost (31 Mar. 2023)
• Your Health: Bloodless heart surgery (31 Mar. 2023)
• Twins facing life-threatening condition go home healthy thanks to OHSU fetal surgery team (30 Mar. 2023)
• FDA will refuse new medical devices for cybersecurity reasons on Oct. 1 (29 Mar. 2023) | Related:
  • Guidance gives FDA authority to reject devices due to poor cybersecurity (29 Mar. 2023)
• CDC clarifies Covid booster policy, recommending single bivalent shot (29 Mar. 2023)
• FDA floats oncology authorization shake-up, pitching 'one-trial' model for accelerated and full approval (27 Mar. 2023) | Related:
  • Clinical Trial Considerations to Support Accelerated Approval of Oncology Therapeutics Guidance for Industry March 2023)
• Miracle match: Californian and Valley donor meet (29 Mar. 2023)
• Blood transfusions save Chester County mother who experienced rare birthing complications (28 Mar. 2023)
• FDA has granted 510(k) clearance to Advamedica’s hemostat cleared for severe surgical bleeding (27 Mar. 2023)
• 'Live free and die?' The sad state of U.S. life expectancy (25 Mar. 2023) | Related:
  • Woolf SH, Wolf ER, Rivara FP. The new crisis of increasing all-cause mortality in US children and adolescents. JAMA. 2023 Mar 28;329(12):975-6. (Free full text)
• CDC data: XBB.1.5 responsible for 90% of new COVID-19 cases (24 Mar. 2023)
• FDA outlines plan for digital health technologies for clinical trials (24 Mar. 2023) | Related:
  • Framework for the Use of Digital Health Technologies in Drug and Biological Product Development
• Blood drive set at Church of Jesus Christ of Latter-Day Saints (24 Mar. 2023)
• Best Life: Bloodless heart surgery (23 Mar. 2023)
• White House announces record health insurance enrollment for ACA’s 13th birthday (23 Mar. 2023) | Related:
  • State Fact Sheets: White House lays out devastating consequences of MAGA house Republican plans to gut medicaid and the Affordable Care Act in State-by-state fact sheets (23 Mar. 2023)
• Regulatory update: FDA releases 2022 biological product deviation report summary (22 Mar. 2023) | Related:
  • Biological Product and HCT/P Deviation Reports (Annual Summary for Fiscal Year 2022)
• Locally acquired dengue infections reported in Arizona (22 Mar. 2023) | Related:
  • Kretschmer M, Collins J, Dale AP, et al. Notes From the Field: First evidence of locally acquired dengue virus infection - Maricopa County, Arizona, November 2022. MMWR Morb Mortal Wkly Rep. 2023 Mar 17;72(11):290-1. (Free full text)
• Biden administration plans to break up monopoly power of U.S. organ transplant system (22 Mar. 2023)
• Toledo man's life saved by blood transfusions (22 Mar. 2023)
• Philadelphia woman is one of nation's oldest living sickle cell patients (22 Mar. 2023)
• FDA issues guidance on submission of pharmacogenomic data (21 Mar. 2023)
• AABB urges congress to include laboratory workforce in health care workforce legislation (21 Mar. 2023)
• Candida auris new 'urgent' antimicrobial resistance threat, CDC says (20 Mar. 2023) | Related:
  • Lyman M, Forsberg K, Sexton DJ, et al. Worsening spread of Candida auris in the United States, 2019 to 2021. Ann Intern Med. 2023 Mar 21. Epub ahead of print.
• Maternal deaths rose dramatically during pandemic, CDC study shows (16 Mar. 2023) | Related:
  • Hoyert DL.Maternal mortality rates in the United States, 2021. NCHS Health E-Stats. 2023.

Industry news\\

• AbbVie, Janssen Biotech, BeiGene: AbbVie, J&J pull 2 Imbruvica accelerated approvals in lymphoma, giving way to AZ and BeiGene (7 Apr. 2023)
• Advamedica: See USA above
• AstraZeneca: AstraZeneca acalabrutinib receives approval in China for relapsed/refractory mantle cell lymphoma (23 Mar. 2023)
• Bristol Myers Squibb: See General news above
• Caribou Biosciences: See USA above
• Gamida Cell: After going all-in on blood cancer therapy, Gamida Cell scores big win at FDA (17 Apr. 2023)
• General news: Blood transfusion devices market to witness huge growth by 2030 | Macopharma, Becton Dickinson, B.Braun, Terumo, Abbott (12 Apr. 2023)
• General news: Plasma fractionation market will reach USD 50,638 million by 2030, says P&S Intelligence (28 Mar. 2023)
• Glenmark Pharmaceuticals: See USA above
• Hemex: Hemex awarded $3M to bring Gazelle diagnostic test to US (28 Mar. 2023)
• Ichnos Science: Ichnos Science's ISB 1442 lands FDA orphan drug status for R/R multiple myeloma (22 Mar. 2023) | Related:
  • Ichnos Sciences receives orphan drug designation for first-in-class bispecific (CD38 x CD47) antibody innate cell modulator, ISB 1442 (21 Mar. 2023)
• Magnolia Medical: Magnolia Medical expands Steripath^® Micro Initial Specimen Diversion Device^® (ISDD^®) product family with new FDA 510(k) clearance (11 Apr. 2023)
• Midge Medical, Institut Pasteur de Dakar: Midge Medical partners with the Institut Pasteur de Dakar to offer an easy and affordable innovative detection solution for Marburg virus (4 Apr. 2023)
• Moderna: Moderna says it hopes to offer new vaccines for cancer, heart disease, and other conditions by 2030 (11 Apr. 2023)
• Molecular Templates: See USA above
• NITI Aayog: See India above
• QuidelOrtho: QuidelOrtho announces the formation of the International QuidelOrtho Women’s Leadership Network - QWLN (28 Mar. 2023)
• Rallybio: Rallybio announces clinical proof-of-concept results for RLYB211, an anti-HPA-1a polyclonal antibody for the prevention of fetal and neonatal alloimmune thrombocytopenia - FNAIT (6 Apr. 2023) | Related:
  • Geisen C, Kjaer M, Fleck E, et al. An HPA-1a-positive platelet-depleting agent for prevention of fetal and neonatal alloimmune thrombocytopenia: a randomized, single-blind, placebo-controlled, single-center, phase 1/2 proof-of-concept study. J Thromb Haemost. 2023 Apr;21(4):838-49. Epub 2022 Dec 22. (Open access) | PubMed abstract
• Roxane Laboratories, Takeda Pharmaceuticals: See General news above
• Taro Pharmaceutical: See Canada above
• Vertex/CRISPR: Vertex/CRISPR’s gene editing therapy cost effective at $1.9 million ­ pricing review group (12 Apr. 2023)
• Vitestro:Vitestro to supply autonomous blood drawing devices to OLVG Lab (13 Apr. 2023)

Infectious diseases in the news##

• COVID-19: See General news, USA above
• Candida auris: See USA above
• Dengue fever: See USA above
• Fungal infection: See USA above and Journals below
• HCV, HIV: See General news, UK above and Journals below
• HBV, HCV, HIV: See General news above
• HCV: See General news above and Journals below
• HIV: See General news and India above
• Marburg virus: See General news, USA above and Journals below
• Trichomonas vaginalis: See General news and Journals below

Resource Library

• CANADA:
  • CBS: Learning about organ and tissue donation portal (K-12) | Portal created by CBS collaborating with Canada's organ/tissue donation and transplant organizations.
  • CBS: Funded research projects
  • CBS: FAQ: Information for health professionals on safety of transfused blood collected from COVID-19-vaccinated donors
  • CSTM 2023 Conference, Montréal (25-28 May, 2023)
  • CSMLS LabCon 2023 (Whistler, BC May 26-28, 2023)
  • Héma-Québec: Multiple videos on [blood donation, plasma donation, stem cell donation, mother's milk donation, sickle cell anemia & more]
  • The OrbCon Report April 2023 | In this issue:
    • • Transfusion Reaction Reporting
      • Canadian Society For Transfusion Medicine (CSTM) Conference 2022- May 26-29th
      • Celebrating National Medical Laboratory Week 
      • Register: CSTM 2022 Annual Conference
      • Register: Perinatal Consensus Conference
      • Featured Resource: IVIG Infusion Guide
      • Coming Soon: Transfusion Medicine Education Web Conference Archive Video
      • Upcoming Event: University of Toronto Transfusion Medicine Rounds
    • • ORBCoN Fall (MHP) Symposium
      • Register: Transfusionists Talk: Transfusion Made Bloody Easy
      • Register: Provincial Bedside Audit of Blood Administration
• PBCO:
  • Stay tuned...
• Australia/NZ:
  • Australian and New Zealand Society of Blood Transfusion:ANZSBT (Multiple guidelines)
  • Australian Blood Matters Program (Multiple resources)
  • Blood Safe e-Learning Australia
• Ireland (HSE): Blood transfusion leaflets (In 7 languages)
• ISBT:
  • ISBT Code of Ethics (Available in 8 languages)
  • Identify critical elements of a scientific manuscript review ( Dr. Ziggy Szczepiorkowski webinar: 47:58 min.)
  • ISBT Transfusion Reactions E-learning Module
  • ISBT Patient Blood Management Resources
  • ISBT Blood transport container validation guidelines (6 pp. pdf)
• EBA: European Blood Alliance (Position papers and fact sheets)
• UK:
  • NEW  British Society for Haematology guideline for anticoagulant management of pregnant individuals with mechanical heart valves (1 Apr. 2023)
  • JPAC
    • Transfusion Information for Patients
    • Consent for Blood Transfusion - Guidance for Healthcare Practitioners in the UK
    • Consent for Blood Transfusion
  • NHS:
    • Clinical commissioning policy: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
    • Clinical panel report: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
    • Clinical priorities advisory group summary report: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
    • Evidence review: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
    • Engagement report: Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
    • Equality and Health Inequalities Impact Assessment (EHIA): Treatment of iron overload for transfused and non-transfused patients with chronic inherited anaemias (all ages)
• British Society for Haematology (Multiple guidelines)
• NHSBT: Blood Assist | Covers 8 core stages of blood administration, including positive patient identification, consent, compatibility, transfusion reactions and more.
• SHOT:
  • Stay tuned...
• USA (AABB):
  • Monthly podcasts from the Journal Transfusion

  Journals, etc.++

  Free full text papers | * 1 or more Canadian authors

• Free sample journal issues:
  • Lancet Group publishes the latest monkeypox-related content in all Lancet journals | All monkeypox content is free to access.
  • Open access journal: The Lancet Digital Health 2019 May;1(1):e1-e44.
  • Open access journal: Hematology, Transfusion and Cell Therapy, Journal of the Brasilian Association of Hematology, Hemotherapy and Cell Therapy (ABHH)
  • Transfus Med Hemother 2019 Oct; 46(5): Many open access articles
  • Open access journal (May 2020): The Lancet Microbe
• Adler A, Biggs MA, Kaller S, et al. Changes in the frequency and type of barriers to reproductive health care between 2017 and 2021. JAMA Netw Open. 2023 Apr 3;6(4):e237461. | PubMed abstract
• Akchurin O, Molino AR, Schneider MF, et al. Longitudinal relationship between anemia and statural growth impairment in children and adolescents with nonglomerular CKD: Findings From the Chronic Kidney Disease in Children (CKiD) Study. Am J Kidney Dis. 2023 Apr;81(4):457-465.e1. Epub 2022 Dec 5.
• Alderete JF, Chan H. Point-of-care diagnostic for Trichomonas vaginalis, the most prevalent, non-viral sexually transmitted infection. Pathogens. 2023 Jan 3;12(1):77. | PubMed abstract
• Al-Khaffaf A, Frattini F, Sissa C, et al. Dabigratan-related acute agranulocytosis. (Letter to the editor) Blood Transfus. 2019 Mar;17(2):163-4. Epub 2019 Jan 21.
• * Alshalani A, Beuger BM, van Bruggen R, et al. Cultured CD71 erythroid cells modulate the host immune response. Transfus Med. 2023 Mar 15. Epub ahead of print. | PubMed abstract
• Anne PB, Gupta A, Misra S, et al. Economic evaluation of nucleic acid testing for screening of blood donations for thalassemia patients (ECONAT) in Western India. Indian J Hematol Blood Transfus. 2023 Apr;39(2):317-24. Epub 2022 Sep 5.
• Arditi B, Emont J, Friedman AM, et al. Deliveries among patients with maternal hepatitis C virus infection in the United States, 2000-2019. Obstet Gynecol. 2023 Apr 1;141(4):828-36. Epub 2023 Mar 9.
• Artenie A, Stone J, Fraser H, et al.; HIV and HCV Incidence Review Collaborative Group. Incidence of HIV and hepatitis C virus among people who inject drugs, and associations with age and sex or gender: a global systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2023 Mar 27:S2468-1253(23)00018-3. Epub ahead of print. | PubMed abstract
• Bergauer L, Braun J, Roche TR, et al. Avatar-based patient monitoring improves information transfer, diagnostic confidence and reduces perceived workload in intensive care units: computer-based, multicentre comparison study. Sci Rep. 2023 Apr 11;13(1):5908. | PubMed abstract
• Beverly A, Ong G, Kimber C, et al. Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Feb 17;2(2):CD013649. | PubMed abstract
• Blaine KP, Dudaryk R, Milne AD, et al. Training anesthesiology residents to care for the traumatically injured in the United States. Anesth Analg. 2023 May 1;136(5):861-76. Epub 2023 Apr 14. | PubMed abstract
• Blokzijl J, Pisters MF, Veenhof C, et al. Functional decline in persons with haemophilia and factors associated with deterioration. Haemophilia. 2023 Mar 28. Epub ahead of print. | PubMed abstract
• Bonroy C, Vercammen M, Fierz W, et al.; European Federation of Laboratory Medicine (EFLM) Working Group “Autoimmunity Testing,” the European Autoimmune Standardization Initiative (EASI) and International Consensus on Antinuclear Antibody Patterns (ICAP). Detection of antinuclear antibodies: recommendations from EFLM, EASI and ICAP. Clin Chem Lab Med. 2023 Mar 29. Epub ahead of print. | PubMed abstract
• Bouzat P, Charbit J, Abback PS, et al.; PROCOAG Study Group. Efficacy and safety of early administration of 4-factor prothrombin complex concentrate in patients with trauma at risk of massive transfusion: The PROCOAG Randomized Clinical Trial. JAMA. 2023 Mar 21:e234080. Epub ahead of print. | PubMed abstract
• Bringhen S, Pour L, Benjamin R, et al. Ixazomib versus placebo as post-induction maintenance therapy in newly diagnosed multiple myeloma patients: an analysis by age and frailty status of the TOURMALINE-MM4 study. Clin Lymphoma Myeloma Leuk. Published online March 28, 2023.
• Bryan LJ, Casulo C, Allen PB, et al. Pembrolizumab added to ifosfamide, carboplatin, and etoposide chemotherapy for relapsed or refractory classic hodgkin lymphoma: A multi-institutional phase 2 investigator-initiated nonrandomized clinical trial. JAMA Oncol. 2023 Mar 16:e227975. Epub ahead of print.
• * Chassé M, Fergusson DA, Tinmouth A, et al. Effect of donor sex on recipient mortality in transfusion. N Engl J Med. 2023 Apr 13;388(15):1386-95.
• Chatterjee P, Alagumalai K, Panneerselvam S. Role of acute normovolemic hemodilution in pregnancy for emergency cesarean section in a patient with Bombay blood group. Cureus 15(4): e37995. Epub 22 April 2023.
• Cybulski C, Zamani N, Kluzniak W, et al. Variants in ATRIP are associated with breast cancer susceptibility in the Polish population and UK Biobank. Am J Hum Genet. 2023 Apr 6;110(4):648-62. Epub 2023 Mar 27.
• Ershler WB, De Castro LM, Pakbaz Z, et al. Hemoglobin and end-organ damage in individuals with sickle cell disease. Curr Ther Res Clin Exp. 2023 Feb 23;98:100696. | PubMed abstract
• Feher A, Menashe I, Miller J, Wolf E. Personalized letters and emails increased marketplace enrollment among households eligible for zero-premium plans. Health Aff (Millwood). 2023 Apr;42(4):585-93.
• Ferro C, Benjumea D, Dieguez G, et al. Blood transfusion and transplant rates among Medicare patients with dialysis-dependent CKD and hyporesponse to ESAs. Presented at: NKF 2023 Spring Clinical Meetings, April 11-15, Austin, Texas. Poster 180.
• Fiedler SA, Henseler O, Hoffelner M, et al. Monitoring blood supply in Germany: A regulatory perspective. Transfus Med Hemother. 2023 Jan 18;50(2):129-34. | PubMed abstract
• Fioredda F, Skokowa J, Tamary H, et al. The European Guidelines on Diagnosis and Management of Neutropenia in Adults and Children: A Consensus Between the European Hematology Association and the EuNet-INNOCHRON COST Action. Hemasphere. 2023 Mar 30;7(4):e872. | PubMed abstract
• * Fisher WA, Kohut T, Woo H, Haw J. Alternatives to blood donor deferral of gay, bisexual, and other men who have sex with men: Acceptability of screening the sexual risk behavior of all blood donors. Transfusion. 2023 Mar;63(3):531-40. Epub 2023 Jan 13. | PubMed abstract
• Fonseca R, Arribas M, Wiedmeier-Nutor JE, et al. Integrated analysis of next generation sequencing minimal residual disease (MRD) and PET scan in transplant eligible myeloma patients. Blood Cancer J. 2023 Mar 6;13(1):32.| PubMed abstract
• Fuchizaki A, Yasui K, Hayashi T, et al. A novel quantitative method to evaluate the contribution of platelet products to white thrombus formation in reconstituted blood under flow conditions. Vox Sang. 2023 Mar 2. Epub ahead of print. | PubMed abstract
• Gabriel C, Marks DC, Henschler R, et al. Eye drops of human origin-Current status and future needs: Report on the workshop organized by the ISBT Working Party for Cellular Therapies. Vox Sang. 2023 Feb 27. Epub ahead of print | PubMed abstract
• Geisen C, Kjaer M, Fleck E, et al. An HPA-1a-positive platelet-depleting agent for prevention of fetal and neonatal alloimmune thrombocytopenia: a randomized, single-blind, placebo-controlled, single-center, phase 1/2 proof-of-concept study. J Thromb Haemost. 2023 Apr;21(4):838-49. Epub 2022 Dec 22. | PubMed abstract
• George KM, Maillard P, Gilsanz P, et al. Association of early adulthood hypertension and blood pressure change with late-life neuroimaging biomarkers. JAMA Netw Open. 2023 Apr 3;6(4):e236431. | PubMed abstract
• Giménez-Richarte Á, Ortiz de Salazar MI, Giménez-Richarte MP, et al. Pathogen inactivation methods to prevent transfusion-transmissible arboviruses: A systematic review and meta-analysis. Trop Med Int Health. 2023 Apr;28(4):262-74. Epub 2023 Mar 14. | PubMed abstract
• Gnanaraj J, Basavarajegowda A, Kayal S, et al. Optimising platelet usage during the induction therapy of acute myeloid leukaemia: Impact of physician education. Transfus Med. 2023 Mar 21. Epub ahead of print.
• Greenfield A, Lamb DR, Gu X, et al. Biophysical analysis and preclinical pharmacokinetics-pharmacodynamics of tangential flow filtration fractionated polymerized human hemoglobin as a red blood cell substitute. Biomacromolecules. 2023 Apr 10;24(4):1855-70. Epub 2023 Mar 6.
• Gupta P, Deo S, Ray MD, et al. A prospective study evaluating perioperative quality metrics of cancer surgery: Experience from a tertiary care cancer centre in India. J Surg Oncol. 2023 Apr 10. Epub ahead of print.
• * Hage D, Pyra K, McCudden C, Padmore R. Rh(D) immune globulin administration in pregnancy: Retrospective audit of patient safety events followed by targeted educational intervention with Bayesian analysis. Transfus Med. 2023 Mar 1. Epub ahead of print. | PubMed abstract
• Hamer MJ, Houser KV, Hofstetter AR, et al; RV 507 Study Team. Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial. Lancet. 2023 Jan 28;401(10373):294-302.
• Hatoum AS, Colbert SMC, Johnson EC, et al. Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders. Nat. Mental Health 1, 210­223 (2023). Epub 22 Mar. 2023.
• Henricks LM, Huisman EJ, Lopriore E, et al. Acute haemolytic transfusion reaction after transfusion of fresh frozen plasma in a neonate-preventable by using solvent/detergent-treated pooled plasma? Transfus Med. 2023 Apr;33(2):174-8. Epub 2022 Oct 18. |
• Hess A, Byerly S, Lenart E, et al. Risk factors for clostridium difficile infection in general surgery patients. Am J Surg. 2023 Jan;225(1):118-21. Epub 2022 Sep 21.
• Holman A, McKeown E, Quinn M, et al. Medical malpractice claims in Hepatology: Rates, reasons, and results. Hepatol Commun. 2023 Apr 14;7(5):e0122. | PubMed abstract
• Hoyert DL.Maternal mortality rates in the United States, 2021. NCHS Health E-Stats. 2023.
• Hunnicutt J, Ma L, Mu G, et al. Red blood cell (RBC) transfusion use varies by baseline hemoglobin (Hb) and is associated with post-transfusion hyperkalemia and hospitalization within 30 days in US patients with stage 3­5 CKD and anemia. Poster #182. Abstract of a poster presented at the National Kidney Foundation Spring Clinical Meetings 2023; April 11-15, 2023; Austin, Texas.
• Iannizzi C, Chai KL, Piechotta V, et al. Convalescent plasma for people with COVID-19: a living systematic review. Cochrane Database Syst Rev. 2023 Feb 1;2(2):CD013600. | PubMed abstract
• Inoue K, Tsugawa Y, Mayeda ER, Ritz B. Association of daily step patterns with mortality in US adults. JAMA Netw Open. 2023 Mar 1;6(3):e235174. | PubMed abstract
• Jacko G, Green A, Lycett L, et al. Evaluation of two temperature storage conditions for full blood count samples from Lifeblood's donors. Transfus Med. 2023 Mar 2. Epub ahead of print. | PubMed abstract
• Jadwin DF, Fenderson PG, Friedman MT, et al. Determination of unnecessary blood transfusion by comprehensive 15-hospital record review. Jt Comm J Qual Patient Saf. 2023 Jan;49(1):42-52. Epub 2022 Nov 8. | PubMed abstract
• Johnson PCC, Dhawale TM, Newcomb RA, et al. Longitudinal patient-reported outcomes in patients receiving chimeric antigen receptor T-cell therapy. Blood Adv. 2023 Mar 30:bloodadvances.2022009117. Epub ahead of print.
• Kakkar B, Melinkeri S, Narawade S, et al. Hemolysis during therapeutic plasma exchange: A rare phenomena. Transfus Med. 2023 Mar 1. Epub ahead of print.
• Khalaji A, Ajam A, Sheikhy A, et al. Mortality across the spectrum of hemoglobin level in patients undergoing surgical coronary revascularization. Clin Cardiol. 2023 Mar 23. Epub ahead of print. | PubMed abstract
• Kretschmer M, Collins J, Dale AP, et al. Notes From the Field: First evidence of locally acquired dengue virus infection - Maricopa County, Arizona, November 2022. MMWR Morb Mortal Wkly Rep. 2023 Mar 17;72(11):290-1.
• Lang EA, An A, Finn S, et al. Epidemiology of platelet transfusions in hospitalized children: A pediatric hospital information system database study. Hosp Pediatr. 2023 Apr 1;13(4):283-92. | PubMed abstract
• * Lee DS, Straus SE, Farkouh ME, et al.; COACH Trial Investigators. Trial of an intervention to improve acute heart failure outcomes. N Engl J Med. 2023 Jan 5;388(1):22-32. Epub 2022 Nov 5.
• * Lenet T, Skanes S, Tropiano J, et al. Patient perspectives on intraoperative blood transfusion: A qualitative interview study with perioperative patients. Transfusion. 2023 Feb;63(2):305-14. Epub 2023 Jan 10. | PubMed abstract
• Li Z, Wang Y, Sun M, et al. Application of droplet digital PCR combined with TaqMan real-time PCR in Dombrock blood group genotyping in Northwest China. Vox Sang. 2023 Apr 4. Epub ahead of print. | PubMed abstract
• * Li W, William N, Acker JP. Donor sex, pre-donation hemoglobin, and manufacturing affect CD71⁺ cells in red cell concentrates. Transfusion. 2023 Mar;63(3):601-9. Epub 2023 Jan 19.
• Loriamini M, Lewis-Bakker MM, Frias Boligan K, et al. Small molecule drugs that inhibit phagocytosis. Molecules. 2023 Jan 12;28(2):757. | PubMed abstract
• Lyman M, Forsberg K, Sexton DJ, et al. Worsening spread of Candida auris in the United States, 2019 to 2021. Ann Intern Med. 2023 Mar 21. Epub ahead of print.
• Mahender A, Chavan SS, Saroa R, Chauhan M. Recent advances in geriatric anaesthesia. Indian J Anaesth. 2023 Jan;67(1):152-8. Epub 2023 Jan 21. | PubMed abstract
• Mangala C, Fokam J, Maulot-Bangola D, et al. Genetic diversity of the human immunodeficiency virus of type 1 in Gabonese transfusional settings. BMC Infect Dis. 2023 Mar 30;23(1):191. | PubMed abstract
• Moore CM, D'Amore A, Fustolo-Gunnink S, et al.; PlaNeT2 MATISSE. Two-year outcomes following a randomised platelet transfusion trial in preterm infants. Arch Dis Child Fetal Neonatal Ed. 2023 Feb 21:fetalneonatal-2022-324915. Epub ahead of print. | PubMed abstract
• Mora D, Mateo J, Nieto JA, etal.; and the Registro Informatizado de Enfermedad TromboEmbólica (RIETE) Investigators. Machine learning to predict major bleeding during anticoagulation for venous thromboembolism: possibilities and limitations. Br J Haematol. 2023 Mar 21. Epub ahead of print. | PubMed abstract
• Morelli MK, Kloosterboer A, Omar AF. Pseudomonas aeruginosa corneal ulcer associated with artificial tears eye drops. JAMA Ophthalmol. 2023 Mar 22. Epub ahead of print.
• Murata T, Otsuka R, Sasaki A, et al. Induction of allograft tolerance by adoptive transfer of donor B cells: an immune regulatory strategy for transplantation using MHC-matched iPS cells. Int Immunol. 2023 Apr 13:dxad008. Epub ahead of print.
• * O'Brien SF, Caffrey N, Yi QL, et al. Cross-Canada variability in blood donor SARS-CoV-2 seroprevalence by social determinants of health. Microbiol Spectr. 2023 Feb 14;11(1):e0335622. Epub 2023 Jan 10. | PubMed abstract
• * Oliero M, Hajjar R, Cuisiniere T, et al. Prevalence of pks + bacteria and enterotoxigenic Bacteroides fragilis in patients with colorectal cancer. Gut Pathog. 2022 Dec 28;14(1):51. | PubMed abstract
• Ottonello A, Wyllie JA, Yahiaoui O, et al. Shapeshifting bullvalene-linked vancomycin dimers as effective antibiotics against multidrug-resistant gram-positive bacteria. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2208737120. Epub 2023 Apr 3.
• Park S, Belfoul AM, Rastelli M, et al. Maternal low-calorie sweeteners consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway. JCI Insight. 2023 Apr 4:e156397. Epub ahead of print. | PubMed abstract
• Pelcovits A, Barth P, Reagan JL, et al. Ixazomib, oral metronomic cyclophosphamide, and dexamethasone for first-line treatment of multiple myeloma: A Phase II Brown University Oncology Group Study. Oncologist. 2023 Mar 21:oyad017. Epub ahead of print. | PubMed abstract
• Piri S. Pay-for-performance programs effectiveness in healthcare: the case of the end-stage renal disease quality incentive program. Eur J Health Econ. 2023 Mar 26. Epub ahead of print.
• Purtell SR, Thornhill D, Loi M, et al. Risk factors for venous thromboembolic events in children with acute musculoskeletal infections. J Pediatr Orthop. 2023 Mar 16. Epub ahead of print.
• * Radauer-Plank AC, Diesch-Furlanetto T, Schneider M, et al. Desire for biological parenthood and patient counseling on the risk of infertility among adolescents and adults with hemoglobinopathies. Pediatr Blood Cancer. 2023 Apr 14:e30359. Epub ahead of print. | PubMed abstract
• Ramos SA, Armitage LH, Morton JJ, et al. Generation of functional thymic organoids from human pluripotent stem cells. Stem Cell Reports. 2023 Mar 14:S2213-6711(23)00060-7. Epub ahead of print. | PubMed abstract
• Rikard SM, Strahan AE, Schmit KM, et al. Chronic pain among adults - United States, 2019-2021. MMWR Morb Mortal Wkly Rep. 2023 Apr 14;72(15):379-85. | PubMed abstract
• Safran T, Vorstenbosch J, Viezel-Mathieu A, et al. Topical tranexamic acid in breast reconstruction: A double-blind, rRandomized controlled trial. Plast Reconstr Surg. 2023 Feb 27:e010322. Epub ahead of print.
• Saltzmann C. How to convert whole-blood donors to plasma donors: An investigation of the mechanisms of awareness of need for plasma and donors' perception of response efficacy. Transfusion. 2023 Apr 1. Epub ahead of print. | PubMed abstract
• Samukange WT, Kafere C, Heinrich K, et al. Strengthening blood regulatory systems to tackle Africa's unmet needs for blood and blood products. Transfus Med Hemother. 2022 Dec 22;50(2):123-8. | PubMed abstract
• Sauta E, Robin M, Bersanelli M, et al. Real-world validation of molecular international prognostic scoring system for myelodysplastic syndromes. J Clin Oncol. 2023 Mar 17:JCO2201784. Epub ahead of print. | PubMed abstract
• Sawadogo S, Nébié K, Traoré C, et al. Prevalence and specificity of red blood cell antibodies in patients transfused in tertiary hospitals in Burkina Faso. Transfus Med. 2023 Mar 22. Epub ahead of print.
• Schain F, Boissin C, Laczik T, et al. Real-world clinical characterization, healthcare resource utilization and productivity loss in chronic graft versus host patients exposed to extracorporeal photopheresis in Sweden. Transfus Apher Sci. 2023 Mar 21:103705. Epub ahead of print. | PubMed abstract
• Seed PT, Brien SB, Oakley LL, et al. Serial prophylactic exchange blood transfusion in pregnant women with sickle cell disease (TAPS-2): statistical and qualitative analysis plan for a randomised controlled feasibility trial. Trials. 2023 Mar 24;24(1):225. | PubMed abstract
• Segaloff HE, Wu K, Shaw S, et al. Notes from the field: Cluster of blastomycosis among neighborhood residents - St. Croix County, Wisconsin, 2022. MMWR Morb Mortal Wkly Rep. 2023 Mar 31;72(13):348-9.
• Sekhar Das S, Chaudhuri K, Mukherjee S. Clinical and immunohematological characterization of autoimmune hemolytic anemia in children. Transfus Apher Sci. 2023 Mar 15:103703. Epub ahead of print. | PubMed abstract
• Sestito LF, To KHT, Cribb MT, et al. Lymphatic-draining nanoparticles deliver Bay K8644 payload to lymphatic vessels and enhance their pumping function. Sci Adv. 2023 Feb 24;9(8):eabq0435. Epub 2023 Feb 24. | PubMed abstract
• Shah NM, Jang HJ, Liang Y, et al. Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements. Nat Genet. 2023 Mar 27. Epub ahead of print. | PubMed abstract
• Shim K, Longtine MS, Abou DS, et al. Cure of disseminated humanl lymphoma with [¹⁷⁷Lu]Lu-ofatumumab in a preclinical model. J Nucl Med. 2023 Apr;64(4):542-8. Epub 2022 Nov 10. | PubMed abstract
• Signorelli C, Wakefield CE, McLoone JK, et al.; ANZCHOG Survivorship Study Group. Childhood cancer survivors' reported late effects, motivations for seeking survivorship care, and patterns of attendance. Oncologist. 2023 Mar 21:oyad004. Epub ahead of print. | PubMed abstract
• Shirzaei Sani E, Xu C, et al. A stretchable wireless wearable bioelectronic system for multiplexed monitoring and combination treatment of infected chronic wounds. Sci Adv. 2023 Mar 24;9(12):eadf7388. Epub 2023 Mar 24. | PubMed abstract
• Soares DMB, Araújo DABS, de Souza JLB, et al. Correlation between ABO blood type, susceptibility to SARS-CoV-2 infection and COVID-19 disease severity: A systematic review. Hematol Transfus Cell Ther. 2022 Nov 30. Epub ahead of print. | PubMed abstract
• Srivastava A, Rangarajan S, Kavakli K, et al. Fitusiran prophylaxis in people with severe haemophilia A or haemophilia B without inhibitors (ATLAS-A/B): a multicentre, open-label, randomised, phase 3 trial. Lancet Haematol. 2023 Mar 29:S2352-3026(23)00037-6. Epub ahead of print.
• Steen Carlsson K, Winding B, Astermark J, et al. High use of pain, depression, and anxiety drugs in hemophilia: more than 3000 people with hemophilia in an 11-year Nordic registry study. Res Pract Thromb Haemost. 2023 Jan 31;7(2):100061. | PubMed abstract
• Swanson K, Wu E, Zhang A, et al. From patterns to patients: Advances in clinical machine learning for cancer diagnosis, prognosis, and treatment. Cell. 2023 Mar 7:S0092-8674(23)00094-6. Epub ahead of print.
• Talboom K, Borstlap WAA, Roodbeen SX,et al.; FIT collaborative group. Ferric carboxymaltose infusion versus oral iron supplementation for preoperative iron deficiency anaemia in patients with colorectal cancer (FIT): a multicentre, open-label, randomised, controlled trial. Lancet Haematol. 2023 Apr;10(4):e250-e260. Epub 2023 Feb 27.
• Tan CCS, Ko KKK, Chen H, et al; SG10K_Health Consortium; Chia M, Nagarajan N. No evidence for a common blood microbiome based on a population study of 9,770 healthy humans. Nat Microbiol. 2023 Mar 30. Epub ahead of print. | PubMed abstract
• Tang ASO, Leong TS, Ong JHL, et al. Cost of treatment for myelofibrosis patients in Ministry of Health Hospitals in Sarawak, Malaysia. Asian Pac J Cancer Prev. 2023 Mar 1;24(3):733-6. | PubMed abstract
• Tantry TP, Karanth H, Anniyappa S, et al. Intravenous oxytocin regimens in patients undergoing cesarean delivery: a systematic review and network meta-analysis of cluster-based groups. J Anesth. 2023 Apr;37(2):278-93. Epub 2022 Nov 16.
• The Lancet Haematology. Haemophilia-unparalleled progress but inadequate access. (Editorial) Lancet Haematol. 2023 Apr;10(4):e235.
• Tosoni G, Ayyildiz D, Bryois J, et al. Mapping human adult hippocampal neurogenesis with single-cell transcriptomics: Reconciling controversy or fueling the debate? Neuron. 2023 Mar 27:S0896-6273(23)00206-4. Epub ahead of print. | PubMed abstract
• Tran MH. Therapeutic modalities in thrombotic thrombocytopenic purpura management among Jehovah's Witness patients: A review of reported cases. Transfus Apher Sci. 2023 Mar 21:103706. Epub ahead of print. | PubMed abstract
• van der Veer HJ, van Aalen EA, Michielsen CMS, et al. Glow-in-the-dark infectious disease diagnostics using CRISPR-Cas9-Based Split luciferase complementation. ACS Cent Sci.2023. Epub 15 Mar. 2023.
• von Heymann C, Lier H, Rosenthal C, Kaufner L. Indications for the use of therapeutic plasma in adult patients. Transfus Med Hemother. 2022 Dec 14;50(2):107-15. | PubMed abstract
• Walker BS, Schmidt RL, Moore RA, et al. Bacterial culture time to detection in platelet components: An evidence synthesis and estimation of detection failures. Transfusion. 2023 Jan;63(1):182-92. Epub 2022 Nov 13.
• Wang C, Sallman DA. Current therapeutic landscape in lower risk myelodysplastic syndromes. Curr Treat Options Oncol. 2023 Mar 25. Epub ahead of print.
• Wang WD, Hu F, Zhou DH, et al. Thalassaemia in China. Blood Rev. 2023 Mar 17:101074. Epub ahead of print. | PubMed abstract
• Wang G, Buckley JP, Bartell TR, et al. Cord Blood insulin concentration and hypertension among children and adolescents enrolled in a US racially diverse birth cohort. Hypertension. 2023 Mar 13. Epub ahead of print.
• Wang R, Shallis RM, Stempel JM, et al. Second malignancies among older patients with classical myeloproliferative neoplasms treated with hydroxyurea. Blood Adv. 2023 Mar 14;7(5):734-43. | PubMed abstract
• Wangi Ngoy Y, Nganga Nkanga MS, Ndelembo Baina G, et al. Critical assessment of transfusional practices in the obstetrics and gynecology department at the University Hospital of Kinshasa. J Blood Med. 2023 Mar 27;14:221-231. | PubMed abstract
• Wellmann S, Hagmann CF, von Felten S, et al.; Erythropoietin for the Repair of Cerebral Injury in Very Preterm Infants (EpoRepair) Investigators. Safety and short-term outcomes of high-dose erythropoietin in preterm infants with intraventricular hemorrhage: The EpoRepair Randomized Clinical Trial. JAMA Netw Open. 2022 Dec 1;5(12):e2244744. | PubMed abstract
• Woolf SH, Wolf ER, Rivara FP. The new crisis of increasing all-cause mortality in US children and adolescents. JAMA. 2023 Mar 28;329(12):975-6.
• Xie Y, Choi T, Al-Aly Z. Risk of death in patients hospitalized for COVID-19 vs seasonal influenza in fall-winter 2022-2023. JAMA. 2023 Apr 6:e235348. Epub ahead of print.
• Xia J, Li Q, Tian Y, et al. An unmanned emergency blood dispatch system based on an early prediction and fast delivery strategy: Design and development study. Comput Methods Programs Biomed. 2023 Mar 26;235:107512. Epub ahead of print. text)
• Xiao J, Yang Q, Gao S, et al. Hemolytic disease of the newborn due to anti-Jra from a Chinese mother with one novel and one classic heterozygous mutation. Transfus Med. 2023 Mar 27. Epub ahead of print.
• Yang J, Xu X, Han S, et al. Comparison of multiple treatments in the management of transplant-related thrombotic microangiopathy: a network meta-analysis. Ann Hematol. 2023 Jan;102(1):31-9. Epub 2022 Dec 22.
• Young G, Srivastava A, Kavakli K, et al. Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with inhibitors (ATLAS-INH): a multicentre, open-label, randomised phase 3 trial. Lancet. 2023 Mar 29:S0140-6736(23)00284-2. Epub ahead of print.
• Zhao J, Han X, Miller KD, et al. Association of the COVID-19 pandemic and changes in patterns of cancer-related mortality in the United States. JCO Oncol Pract. 2023 Apr 11:OP2200522. Epub ahead of print. | PubMed abstract