Monthly newsletter - December 2022

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General

ML model accurately predicts need for massive transfusion during surgery (29 Dec. 2022) | Related:
- Lee SM, Lee G, Kim TK, et al. Development and validation of a prediction model for need for massive transfusion during surgery using intraoperative hemodynamic monitoring data. JAMA Netw Open. 2022 Dec 1;5(12):e2246637. (Free full text) | PubMed abstract
Reflecting on another year with sickle cell disease (23 Dec. 2022)
Infant gene therapy is a breakthrough for Artemis-SCID patients (21 Dec. 2022) | Related:
- Cowan MJ, Yu J, Facchino J, et al. Lentiviral gene therapy for Artemis-deficient SCID. N Engl J Med. 2022 Dec 22;387(25):2344-55.
Researchers identify 28 early signs of CAR T-cell toxicity (20 Dec. 2022) | Related:
- Spanjaart AM, Pennings ERA, Kos M, et al. Development of a core set of patient- and caregiver-reported signs and symptoms to facilitate early recognition of acute chimeric antigen receptor T-cell therapy toxicities. JCO Oncol Pract. 2022 Dec 12:OP2200501. Epub ahead of print. (Free full text) | PubMed abstract
Analysis of bluebird bio's beti-cel for severe ß-thalassemia shows extensive, long-term patient improvement (20 Dec. 2022) | Related:
- Longterm follow-up of subjects with transfusion-dependent ß-thalassemia treated with ex vivo gene therapy
The slow roll-out of the world’s first malaria vaccine (19 Dec. 2022)
Laser-pulsing skin patch goes deep to uncover signs of cancer (19 Dec. 2022) | Related:
- Gao X, Chen X, Hu H, et al. A photoacoustic patch for three-dimensional imaging of hemoglobin and core temperature. Nat Commun. 2022 Dec 15;13(1):7757. (Open access) | PubMed abstract
Geriatric assessment in hematology scale predicts treatment tolerability in older patients with hematological malignancies (16 Dec. 2022) | Related:
- de la Rubia J, González B, Cruz-Jentoft AJ, et al. Geriatric assessment in hematology scale predicts treatment tolerability in older patients diagnosed with hematological malignancies: The RETROGAH study. J Geriatr Oncol. 2022 Nov 17:S1879-4068(22)00520-3. Epub ahead of print. (Open access) | PubMed abstract
COVID-19 can spread from dead bodies, research suggests (16 Dec. 2022) | Related:
- Saitoh H, Yuko Sakai-Tagawa Y, Nagasawa S, et al. High titers of infectious SARS-CoV-2 in COVID-19 corpses. medRxiv. 2022 Oct 13. Preprint. (Free full text)
Low platelet counts linked with greater symptom burden in myelofibrosis (16 Dec. 2022) | Related:
- Palmer JM, Gerds AT, Harrison C, et al. Differential impact of thrombocytopenia and anemia on myelofibrosis (MF) symptom burden. Blood. 2022;140(suppl 1):3938-40.
Imaging method yields highly accurate and precise values of radionuclide organ uptake (16 Dec. 2022)
Changing heart cell programming can reverse the lasting damage caused by heart attacks (16 Dec. 2022) | Related:
- Tani H, Sadahiro T, Yamada Y, et al. Direct reprogramming improves cardiac function and reverses fibrosis in chronic myocardial infarction. Circulation. 2022 Dec 12. Epub ahead of print. (Free access) | PubMed abstract
Can stem cells improve shoulder surgery? (16 Dec. 2022) | Related:
- Fang F, Xiao Y, Zelzer E, et al. A mineralizing pool of Gli1-expressing progenitors builds the tendon enthesis and demonstrates therapeutic potential. Cell Stem Cell. 2022 Dec 1;29(12):1669-1684.e6.
Ebola vaccines spur lasting immunity in children and adults, trials show (15 Dec. 2022) | Related:
- PREVAC Study Team, Kieh M, Richert L, et al. Randomized trial of vaccines for Zaire ebola virus disease. N Engl J Med. 2022 Dec 14. Epub ahead of print. (Free full text) | PubMed abstract
National registry may reduce mortality among alloimmunized people with sickle cell disease (15 Dec. 2022)
Point-of-care biosensor rapidly detects oral cancer (14 Dec. 2022) | Related:
- Minghan Xian M, Stephany JL, Chiu C-W, et al. High sensitivity CIP2A detection for oral cancer using a rapid transistor-based biosensor module. J Vac Sci Technol B 2022. Epub 13 Dec. 2022.
Swiss naturopath launches international blood bank for the unvaccinated (14 Dec. 2022) | Related:
- Canadian Blood Services: COVID-19 vaccines and blood donation | Blood from vaccinated donors is safe for patients
Gene therapy confers durable benefits for patients with beta-thalassemia (14 Dec. 2022) | Related:
- 3665 Long-term patient-reported outcomes following treatment with betibeglogene autotemcel in patients with transfusion-dependent ß-thalassemia (Oral & poster abstracts at 64th ASH Annual Meeting)
- 2348 Long term outcomes of 63 patients with Ttransfusion-dependent ß-thalassemia (TDT) followed up to 7 years post-treatment with betibeglogene autotemcel (beti-cel) gene therapy and exploratory analysis of predictors of successful treatment outcomes in phase 3 trials (Oral & poster abstracts at 64th ASH Annual Meeting)
WHO-commissioned study makes strong health and economic argument for investing in new TB vaccines (13 Dec. 2022)
Three data trends guiding cost-saving laboratory logistics strategies and benchmarks (13 Dec. 2022) | Related:
- Report: U.S. hospitals face worst year financially since start of COVID-19 pandemic, jeopardizing access to patient care (15 Sept. 2022)
Smartphone-connected device uses light to detect malaria in 10 seconds (13 Dec. 2022) | Related:
- Garcia GA, Kariyawasam TN, Lord AR, et al. Malaria absorption peaks acquired through the skin of patients with infrared light can detect patients with varying parasitemia. PNAS Nexus 2022 Dec. 7. Epub 7 Dec. (Free to read as .pdf)
New episode of transfusion monthly podcast focuses on hemostatic function of cold-stored platelets (13 Dec. 2022) | Related:
- Cold-stored platelets in a bleeding model (Monthly podcast)
- Nogawa M, Watanabe N, Koike T, et al. Hemostatic function of cold-stored platelets in a thrombocytopenic rabbit bleeding model. Transfusion. 2022 Nov;62(11):2304-13. Epub 2022 Sep 30.
Pediatric hodgkin lymphoma survivors experience accelerated epigenetic aging (13 Dec. 2022) | Related:
- 902 Epigenetic age acceleration and neurocognitive function among long-term survivors of pediatric hodgkin lymphoma: A report from the St. Jude Lifetime Cohort (Oral & poster abstracts at 64th ASH Annual Meeting)
Cancer patients unruffled by whole-body MRI per se (13 Dec. 2022) | Related:
- Mazzocco K, Busacchio D, Summers PE, et al. Is whole-body magnetic resonance imaging a source of anxiety in oncological patients? Cancer Rep (Hoboken). 2022 Dec 9:e1737. Epub ahead of print. (Open access) | PubMed abstract
WHO member states commit to producing a pandemic accord in 2023 (12 Dec. 2022) | Related:
- WHO Member States agree to develop zero draft of legally binding pandemic accord in early 2023 (7 Dec. 2022; WHO news release)
Experimental CAR-T safe, ‘highly effective’ for certain patients with T-cell malignancies (12 Dec. 2022) | Related:
- 980 Analysis of 53 patients with relapsed or refractory (R/R) T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) treated with CD7-targeted CAR-T cell therapy (Oral & poster abstracts at 64th ASH Annual Meeting)
Team undertakes study of two-dimensional transition metal chalcogenides (12 Dec. 2022) | Related:
- Wang K, Xu W, Zhang W, et al. Bio-inspired water-driven electricity generators: From fundamental mechanisms to practical applications. Nano Research Energy, 2022. Epub 30 Nov. 2022. (Open access)
Teva Pharmaceutical's low-dose lenalidomide reduces risk of transfusion dependency, provides clonal response and safety benefits in MDS (12 Dec. 2022) | Related:
- Cadenas FL, Lumbreras E, Gonzalez T, et al. Evaluation of lenalidomide (len) vs placebo in non-transfusion dependent low risk del(5q) MDS patients. final results of Sintra-REV phase III international multicenter clinical trial. Blood. 2022;140(suppl 1):11091111.
Gene therapy may be equitable therapeutic option for sickle cell disease in US (11 Dec. 2022)
Meet MEDi: a robot designed to help children in hospital manage pain, anxiety (11 Dec. 2022) | Related:
- Gates M, Hartling L, Shulhan-Kilroy J, et al. Digital technology distraction for acute pain in children: A meta-analysis. Pediatrics. 2020 Feb;145(2):e20191139. Epub 2020 Jan 22. (Free full text) | PubMed abstract
Gene therapy may be equitable therapeutic option for sickle cell disease in US (11 Dec. 2022)
A cheap new blood test by Elypta can detect 14 types of cancer before they spread (10 Dec. 2022) | Related:
- Bratulic S, Limeta A, Dabestani S, et al. Noninvasive detection of any-stage cancer using free glycosaminoglycans. Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2115328119. Epub 2022 Dec 5. (Free full text) | PubMed abstract
Pokey patch painlessly monitors drug levels in patients' bloodstreams (8 Dec. 2022) | Related:
- Lin S, Cheng X, Zhu J, et al. Wearable microneedle-based electrochemical aptamer biosensing for precision dosing of drugs with narrow therapeutic windows. Sci Adv. 2022 Sep 23;8(38):eabq4539. Epub 2022 Sep 23. (Free full text) | PubMed abstract
Novartis' Tisa-Cel improves outcomes vs usual care in relapsed or refractory follicular lymphoma (8 Dec. 2022) | Related:
- Salles G, Schuster SJ, Dreyling M, et al. Efficacy comparison of tisagenlecleucel vs usual care in patients with relapsed or refractory follicular lymphoma. Blood Adv. 2022 Nov 22;6(22):5835-43. (Free full text) | PubMed abstract
E-Selectin levels associated with vasculopathy and retinopathy in sickle cell disease (7 Dec. 2022) | Related:
- Agouti I, Masson E, Loundou A, et al. Plasma levels of E-selectin are associated with retinopathy in sickle cell disease. Eur J Haematol. 2022 Nov 21. Epub ahead of print. (Open access) | PubMed abstract
Extreme obesity may increase relapse risk during maintenance therapy in children with leukemia subtype (6 Dec. 2022)
Sarcopenia predicts negative outcomes in newly diagnosed myeloma (6 Dec. 2022) | Related:
- Nandakumar B, Baffour F, Abdallah NH, et al. Sarcopenia identified by computed tomography imaging using a deep learning-based segmentation approach impacts survival in patients with newly diagnosed multiple myeloma. Cancer. 2022 Nov 22. Epub ahead of print.
Lung scarring occurs in up to 11% of patients recovered from COVID, regardless of infection severity (5 Dec. 2022)
When are packed red blood cell transfusions during ECMO beneficial to survival? (5 Dec. 2022) | Related:
- Martucci G, Schmidt M, Agerstrand C, et al.; International ECMO Network (ECMONet). Transfusion practice in patients receiving VV ECMO (PROTECMO): a prospective, multicentre, observational study. Lancet Respir Med. 2022 Oct 11:S2213-2600(22)00353-8. Epub ahead of print.
Encouraging findings in first-in-human clinical trial evaluating HIV vaccine (5 Dec. 2022) | Related:
- Leggat DJ, Cohen KW, Willis JR, et al. Vaccination induces HIV broadly neutralizing antibody precursors in humans. Science. 2022 Dec 2;378(6623):eadd6502. Epub 2022 Dec 2.
Checking blood pressure in a heartbeat, using artificial intelligence and a camera (5 Dec. 2022) | Related:
- Al-Naji A, Fakhri AB, Mahmood MF, Chahl J. Contactless blood pressure estimation system using a computer vision system. Inventions, 2022; 7 (3). (Open access)
Routine use of Kite Pharma's axicabtagene ciloleucel could be cost effective in relapsed/refractory diffuse large B-cell lymphoma (5 Dec. 2022) | Related:
- Kambhampati S, Saumoy M, Schneider Y, et al. Cost-effectiveness of second-line axicabtagene ciloleucel in relapsed refractory diffuse large B-cell lymphoma. Blood. 2022 Nov 10;140(19):2024-36.
Researchers at Institute for Stem Cell Science and Regenerative Medicine report a novel technology to enhance the quality and shelf-life of stored blood. (2 Dec. 2022) | Related:
- Pandey S, Mahato M, Srinath P, et al. Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life. Nat Commun. 2022 Dec 1;13(1):7394. (Open access) | PubMed abstract
World-first trial launches in UK to assess stem cell transplants as first-line MS treatment (2 Dec. 2022) | Related:
- University of Sheffield StarMS Trial
- Brittain G, Coles AJ, Giovannoni G, et al. Autologous haematopoietic stem cell transplantation for immune-mediated neurological diseases: what, how, who and why? Pract Neurol. 2022 Sep 26:pn-2022-003531. Epub ahead of print.
The incidence of antimicrobial resistance among urinary E. coli isolates is increasing in both hospital and community settings in Australia (1 Dec. 2022) | Related:
- Keighley C, van Oijen AM, Brentnall SJ, et al. Multi-year antimicrobial-resistance trends in urine Escherichia coli isolates from both community-based and hospital-based laboratories of an Australian local health district. J Glob Antimicrob Resist. 2022 Nov 24:S2213-7165(22)00251-X. Epub ahead of print. (Free full text) | PubMed abstract
Study reveals wasteosomes as markers of chronic glymphatic system insufficiency (30 Nov. 2022) | Related:
- Riba M, Del Valle J, Molina-Porcel L, et al. Wasteosomes (corpora amylacea) as a hallmark of chronic glymphatic insufficiency. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2211326119. Epub 2022 Nov 21. (Free full text) | PubMed abstract
CATCR-T cell therapy may aid in antiphospholipid syndrome through selective B-cell depletion (30 Nov. 2022)
New prospective study finds that Masimo SpHb^® noninvasive and continuous hemoglobin monitoring can help provide effective blood management in patients undergoing major surgery (30 Nov. 2022) | Related:
- Akdag S, Zengin SU, Cakmak G, et al. Targeted bleeding management guided by non-invasive haemoglobin measurement in surgical patients. J Coll Physicians Surg Pak. 2022 Oct;32(10):1242-8. (Open access) | PubMed abstract
Real-world data supports use of hypomethylating drugs in elderly patients with acute myeloid leukemia (30 Nov. 2022) | Related:
- Molica M, Mazzone C, Niscola P, et al. Identification of predictive factors for overall survival and response during hypomethylating treatment in very elderly ( 75 years) acute myeloid leukemia patients: A multicenter real-life experience. Cancers (Basel). 2022 Oct 6;14(19):4897. (Free full text) | PubMed abstract
Coping strategies linked to distress, quality of life in caregivers of stem cell recipients (29 Nov. 2022) | Related:
- Amonoo HL, Johnson PC, Nelson AM, et al. Coping in caregivers of patients with hematologic malignancies undergoing hematopoietic stem cell transplantation. Blood Adv. 2022 Nov 18:bloodadvances.2022008281. Epub ahead of print. (Free as .pdf) | PubMed abstract
Episode 11B: The effect of trilaciclib in patients receiving chemotherapy for extensive-stage small cell lung cancer treatment (29 Nov. 2022)
Researchers in US and Israel detect fungal DNA in most cancer types found in the human body (28 Nov. 2022) | Related:
- Dohlman AB, Klug J, Mesko M, et al. A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors. Cell. 2022 Sep 29;185(20):3807-3822.e12.
Novel ways to measure glucose levels without drawing blood (23 Nov. 2022) | Related:
- Kim S, Malik J, Seo JM, et al. Subcutaneously implantable electromagnetic biosensor system for continuous glucose monitoring. Sci Rep. 2022 Oct 17;12(1):17395. (Open access) | PubMed abstract
Study challenges “good” cholesterol’s role in predicting heart disease risk (22 Nov. 2022) | Related:
- Zakai NA, Minnier J, Safford MM, et al. Race-dependent association of high-density lipoprotein cholesterol levels with incident coronary artery disease. J Am Coll Cardiol. 2022 Nov 29;80(22):2104-15. (Free full text) | PubMed abstract

Canada

Canadian Blood Services needs blood, plasma donors after storm disruption (27 Dec. 2022)
'Heading into toughest weeks': Blood donors urgently needed (17 Dec. 2022)
Canadian Blood Services needs donors as demand rises over holidays (14 Dec. 2022)
McMaster University's Gordon Guyatt receives 2022 Einstein Foundation individual award for contributions to evidence-based medicine (12 Dec. 2022)

ORBCoN resources:

ORBCoN November newsletter Includes these resources:
- Transfusion related roles for nursing officers
- Blood in a Canadian Armed Forces theatre of operations
- Blood on Board program saving lives and time in first year

Australia

Canberra blood donor centres in urgent need of types A and O amid Christmas holiday shortage (25 Dec. 2022) | A mother whose children's lives were saved by blood donors is urging Australians to roll up their sleeves, to help avert a shortage.
Blood donor centres open between Boxing Day and New Year (24 Dec. 2022)
‘Blood Blitz’ launched to curb Christmas and New Year shortage (20 Dec. 2022) | Australia needs more than 1,800 people a day to donate blood in the next two weeks to prevent a shortage of blood products needed by patients this festive season.
Surgeon and scientist was an organ transplant pioneer (13 Dec. 2022) | Related:
- Sir Peter Morris (Wikipedia entry)

Infectious diseases in the news##

COVID-19: See General news, Cameroon, China, New Zealand, USA above and Journals below
HBV/HCV: See Journals below
HCV/HIV: See UK above
HIV: See General news above
Ebola: See General news above and Journals below
Malaria: See General news, USA above
Monkeypox: See USA above and Journals below

Resource Library

NOTE: Starting January 2021 items in the Resource Library will consist of new or recently added ones. The remaining resources will be in Resource Library Archives. You can also access each country's archived resources individually:
- Australia | Canada | UK | USA
CANADA:
- CBS:Blais-Normandin I, Tordon B, Anani W. Pathogen-reduced buffy coat platelets [Internet]. Ottawa: Canadian Blood Services; 2022 [cited 2022 04 05].
- CBS: Sepsis: The end is just the beginning (3 Feb. 2022) | Related:
  - van der Slikke EC, An AY, Hancock REW, Bouma HR. Exploring the pathophysiology of post-sepsis syndrome to identify therapeutic opportunities. EBioMedicine. 2020 Nov;61:103044. Epub 2020 Oct 8. (Free access) | PubMed abstract
- CBS: Learning about organ and tissue donation portal (K-12) | Portal created by CBS collaborating with Canada's organ/tissue donation and transplant organizations.
- CBS: Funded research projects
- CBS: FAQ: Information for health professionals on safety of transfused blood collected from COVID-19-vaccinated donors
- CBS: COVID-19: Update on organ donation and transplantation services (Links to many resources)
- CBS Clinical Guide to Transfusion:
  - Chapter 5: Concentrates for hemostatic disorders and hereditary angioedema (Updated 6 May 2022)
  - Chapter 11: Trudeau JD, Dawe P, Shih AW. Massive hemorrhage and emergency transfusion. In: Clarke G, Chargé S, editors. Clinical Guide to Transfusion. Canadian Blood Services, 2021 Sept.7 [cited 2021/10/05].
- Héma-Québec: Multiple videos on [blood donation, plasma donation, stem cell donation, mother's milk donation, sickle cell anemia & more]
- ORBCoN:
  - NEW ORBCoN November newsletter Includes these resources:
    - Transfusion related roles for nursing officers
    - Blood in a Canadian Armed Forces theatre of operations
    - Blood on Board program saving lives and time in first year
  - Perinatal Consensus Conference (25 May 2022) | PowerPoint presentations and full audio presentations of each of the lectures are available.
  - Massive Hemorrhage Protocol
  - ORBCoN: Massive Hemorrhage Protocol: 3 simulation videos
  - (3 from GHEST 2021)
- PBCO:
  - NEW 2022 Education Day-Virtual Webinar (23 Sept. 2022) | Also view 'Education Day Recording - Part 3 - Presentation 6, Closing Remarks'
  - Canadian Blood Services, BC & Yukon Region West Nile virus Update, 29 June 2022
Australia/NZ:
- Australian and New Zealand Society of Blood Transfusion:ANZSBT (Multiple guidelines)
- Australian Blood Matters Program (Multiple resources)
- Blood Safe e-Learning Australia
Ireland (HSE): Blood transfusion leaflets (In 7 languages)
ISBT:
- Haemovigilance webinars: Haemovigilance in Australia and beyond (18 Aug./1 Sept./6 Sept.)
- ISBT Code of Ethics (Available in 8 languages)
- Identify critical elements of a scientific manuscript review ( Dr. Ziggy Szczepiorkowski webinar: 47:58 min.)
- ISBT Transfusion Reactions E-learning Module
- ISBT Patient Blood Management Resources
- ISBT Blood transport container validation guidelines (6 pp. pdf)
EBA: European Blood Alliance (Position papers and fact sheets)
UK:
- NEW NHS:
- British Society for Haematology (Multiple guidelines)
- SHOT Bite No. 21 (Dec. 2021)
- NHSBT: Blood Assist | Covers 8 core stages of blood administration, including positive patient identification, consent, compatibility, transfusion reactions and more.
- Live illustrations from the Annual SHOT Symposium 2021 (by Jenny Leonard):
- SHOT:
  - Part 1 (5:11 min. video): Anti-D immunoglobulin errors and immunisation in pregnancy: Insights from SHOT (24 Feb. 2022)
  - Part 2 (5:19 min. video): Anti-D immunoglobulin errors and immunisation in pregnancy: Insights from SHOT (24 Feb. 2022)
  - Transfusion Aide Memoire (2021) | Transfusion essentials for health care professionals
  - Safe transfusions in haemopoietic stem cell transplant recipients (2021)
  - SHOT definitions (Rev. Feb. 2021)
  - TACO pretransfusion checklist (2021)
- NHS: The role of the haematology /transfusion consultant scientist in the delivery of clinical and laboratory haematology services: An education and training solution and a workforce solution. National School of Healthcare Science Haematology Workforce Working Group (September 2020)
- UK SHOT: Animated videos (31 Mar. 2021)
  - Understanding Human Factors in Transfusion Pt 1 (5:55 mins)
  - Understanding Human Factors in Transfusion Pt 2 (7:24 mins)
- SHOT webinar on Haemolytic Transfusion Reactions (12 Mar. 2021) | 55 Min. video
- NHSBT: Patient Blood Management launches Blood Assist app to support and promote safe blood component administration(1 Feb. 2021) | App can be downloaded onto personal devices or centrally in clinical areas.
USA (AABB):
- Monthly podcasts from the Journal Transfusion
- Complimentary copy of the AABB User Guide for the December 2021 Circular of Information for the Use of Human Blood and Blood Components
- Pocket Reference Cards:
  - The latest Covid variant is 1.5 times more contagious than omicron and already circulating in almost half of U.S. states (28 Jan. 2022)
  - Millions of routine vaccinations have been missed amid the Covid-19 pandemic (28 Jan. 2022)
  - Taken from NHSN Biovigilance Component: Hemovigilance Module Surveillance Protocol v2.6 (March 2021)
  - Standard for Surveillance of Complications Related to Blood Donation (Dec. 2014)
  - Severity Grading Tool for Blood Donor Adverse Events (Dec. 2014)WHO resources
WHO resources:
- Introduction to recent WHO publications on Patient Blood Management, Clinical Use of Blood and Haemovigilance Systems (26 July 2022)
- Educational modules on clinical use of blood (198 pp. pdf)
- The Clinical Use of Blood Handbook (221 pp. pdf)
- The clinical use of blood in medicine, obstetrics, paediatrics, surgery and anaesthesia, trauma and burns (344 pp. pdf)

Journals, etc.++

Free full text papers | * 1 or more Canadian authors

Free sample journal issues:
- Lancet Group publishes the latest monkeypox-related content in all Lancet journals | All monkeypox content is free to access.
- Transfus Med Rev 2020 Jan;34(1):1-72. (14 free text articles)
- Brit J Haematol 2017 June;177(6):827-1007. | Special Issue:Low to middle income countries
- Immunohematology (J of American Red Cross): 1988-2017. (Articles in these years are free)
2022 articles from Transfusion Medicine and Hemotherapy (all content accessible) - Issues (Feb., Apr., June, Aug.)
Open access journal: The Lancet Digital Health 2019 May;1(1):e1-e44.
Open access journal: Hematology, Transfusion and Cell Therapy, Journal of the Brasilian Association of Hematology, Hemotherapy and Cell Therapy (ABHH)
Transfus Med Hemother 2019 Oct; 46(5): Many open access articles
Open access journal (May 2020): The Lancet Microbe
Aggarwal R, Charles-Schoeman C, Schessl J, et al.; ProDERM Trial Group. Trial of intravenous immune globulin in dermatomyositis. N Engl J Med. 2022 Oct 6;387(14):1264-78.
Agouti I, Masson E, Loundou A, et al. Plasma levels of E-selectin are associated with retinopathy in sickle cell disease. Eur J Haematol. 2022 Nov 21. Epub ahead of print. | PubMed abstract
Akdag S, Zengin SU, Cakmak G, et al. Targeted bleeding management guided by non-invasive haemoglobin measurement in surgical patients. J Coll Physicians Surg Pak. 2022 Oct;32(10):1242-8. | PubMed abstract
Al-Naji A, Fakhri AB, Mahmood MF, Chahl J. Contactless blood pressure estimation system using a computer vision system. Inventions, 2022; 7 (3).
Amonoo HL, Johnson PC, Nelson AM, et al. Coping in caregivers of patients with hematologic malignancies undergoing hematopoietic stem cell transplantation. Blood Adv. 2022 Nov 18:bloodadvances.2022008281. Epub ahead of print. | PubMed abstract
* Avau B, O D, Veys K, Georgsen J, et al. Systematic reviews on platelet transfusions: Is there unnecessary duplication of effort? A scoping review. Vox Sang. 2022 Dec 1. Epub ahead of print. | PubMed abstract
* Bienz M, Gupta A, Goldstein J, Kennedy J, Lin Y. Severe acute haemolytic transfusion reaction secondary to a plasma incompatible group B platelet transfusion. Transfus Med. 2022 Nov 15. Epub ahead of print.
Bratulic S, Limeta A, Dabestani S, et al. Noninvasive detection of any-stage cancer using free glycosaminoglycans. Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2115328119. Epub 2022 Dec 5. | PubMed abstract
* Breznik JA, Huynh A, Zhang A, et al; other members of the COVID-in-LTC Investigator Group. Cytomegalovirus seropositivity in older adults changes the T cell repertoire but does not prevent antibody or cellular responses to SARS-CoV-2 vaccination. J Immunol. 2022 Nov 15;209(10):1892-1905. | PubMed abstract
Bril V, Szczudlik A, Vaitkus A, et al. A randomized, double-blind, placebo-controlled trial of the corticosteroid-sparing effects of immunoglobulin in myasthenia gravis. Neurology. 2022 Oct 21:10.1212/WNL.0000000000201501. Epub ahead of print. | PubMed abstract
Brittain G, Coles AJ, Giovannoni G, et al. Autologous haematopoietic stem cell transplantation for immune-mediated neurological diseases: what, how, who and why? Pract Neurol. 2022 Sep 26:pn-2022-003531. Epub ahead of print.
Budde LE, Sehn LH, Matasar M, et al. Safety and efficacy of mosunetuzumab, a bispecific antibody, in patients with relapsed or refractory follicular lymphoma: a single-arm, multicentre, phase 2 study. Lancet Oncol. 2022 Aug;23(8):1055-65. Epub 2022 Jul 5.
Cadenas FL, Lumbreras E, Gonzalez T, et al. Evaluation of lenalidomide (len) vs placebo in non-transfusion dependent low risk del(5q) MDS patients. final results of Sintra-REV phase III international multicenter clinical trial. Blood. 2022;140(suppl 1):11091111.
Cajamarca-Barón J, Buitrago-Bohórquez J, Mendoza Orozco JE, et al. Efficacy and safety of intravenous immunoglobulin in patients with lupus nephritis: A systematic review of the literature. Autoimmun Rev. 2022 Nov;21(11):103182. Epub 2022 Aug 24. | PubMed abstract
Chakrabarty JH, Glover J, Schmidt S, et al. Incidence and risk factors for graft failure in the modern era of cord blood transplantation. Vox Sang. 2022 Dec;117(12):1405-10. Epub 2022 Oct 17. | PubMed abstract
Cortes J, Fenaux P, Yee, K, et al. Olutasidenib (FT-2102) induces durable complete remissions in patients with relapsed/refractory mIDH1 acute myeloid leukemia. Results from a planned interim analysis of a phase 2 pivotal clinical trial. Blood. 2022;140(suppl 1):6193-6.
Cowan MJ, Yu J, Facchino J, et al. Lentiviral gene therapy for Artemis-deficient SCID. N Engl J Med. 2022 Dec 22;387(25):2344-55.
Cruz-Chávez DA, López-Pérez BJ, Solórzano-Gómez E, et al. Neurological involvement in pediatric patients with acute leukemia: A retrospective cohort. Children (Basel). 2022 Aug 23;9(9):1268. | PubMed abstract
Curry N, Davenport R, Lucas J, et al. The CRYOSTAT2 trial: The rationale and study protocol for a multi-Centre, randomised, controlled trial evaluating the effects of early high-dose cryoprecipitate in adult patients with major trauma haemorrhage requiring major haemorrhage protocol activation. Transfus Med. 2022 Nov 2. Epub ahead of print.
Czerwinski J, McCarthy A, Herbert D, et al. The complexities of transfusion reactions: Coexistence of a delayed haemolytic transfusion reaction and post-transfusion purpura. Vox Sang. 2022 Nov 25. Epub ahead of print. | PubMed abstract
Degenhardt F, Ellinghaus D, Juzenas S, et al.; STORM Study group, The Humanitas Task Force, The Humanitas Gavazzeni Task Force. Detailed stratified GWAS analysis for severe COVID-19 in four European populations. Hum Mol Genet. 2022 Nov 28;31(23):3945-66. | PubMed abstract
de la Rubia J, González B, Cruz-Jentoft AJ, et al. Geriatric assessment in hematology scale predicts treatment tolerability in older patients diagnosed with hematological malignancies: The RETROGAH study. J Geriatr Oncol. 2022 Nov 17:S1879-4068(22)00520-3. Epub ahead of print. | PubMed abstract
Demeter J, Hamed A, László S, et al. Efficacy and safety of BT595 (10% human intravenous immunoglobulin) in adult patients with chronic immune thrombocytopenia. Transfus Med. 2022 Nov 30. Epub ahead of print. | PubMed abstract
* Dhabangi A, Nankunda J, Okaba V, et al. A cross-sectional study of haemolytic disease of the newborn in Uganda. Vox Sang. 2022 Nov 7. Epub ahead of print.
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