Which of the following are contraindications to receiving IV RhIG to treat ITP?

1. patient with hemoglobin of 100 g/L (10 g/dL)
2. D- negative patient
3. D- positive patient
4. non-splenectomized patient
5. patient with a history of anaphylactic reaction to human globulin

b. D-negative patient
e. patient with a history of anaphylactic reaction to human globulin