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Case Study A2 - Summary of Panels, Selected Cells, and Self Test
 

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Home Case Studies A-Level Case A2: Falling Hemoglobin in a Recently Transfused Patient Case Study A2 - Summary of Panels, Selected Cells, and Self Test
Tuesday, 26 September 2017

Case Study A2 - Summary of Panels, Selected Cells, and Self Test

Exclusion Panel

Rhesus Kell Duffy Kidd MNSs P Lewis Lu Results Comments
C D E c e Cw K k Kpa Fya Fyb Jka Jkb M N S s P1 Lea Leb Lua Gel
IAT*
R1R1 + + 0 0 + 0 0 + 0 0 + 0 + + 0 + 0 +S 0 + +
R1wR1 + + 0 0 + + 0 + 0 + 0 + 0 + + + 0 + 0 + 0
R2R2 0 + + + 0 0 0 + 0 + 0 + 0 + 0 0 + + + 0 0
Ror 0 + 0 + + 0 0 + 0 + 0 + + + + 0 + +S 0 + 0
rr 0 0 0 + + 0 + + 0 + + 0 + 0 + + 0 + 0 + 0 0 1. to exclude ?
r’r + 0 0 + + 0 + + 0 + 0 0 + + 0 + 0 + 0 + 0 2+ anti-C control
r"r 0 0 + + + 0 0 + 0 0 + 0 + 0 + 0 + 0 0 0 0 0 negative control
rr 0 0 0 + + 0 0 + 0 0 + 0 + + 0 + + +S + 0 0 0 2. to exclude ?
rr 0 0 0 + + 0 0 + 0 + + + + 0 + + + +S + 0 0 2+ anti-Jka control
rr 0 0 0 + + 0 0 + 0 + 0 0 + 0 + + 0 + 0 + 0 0 3. to exclude ?
Auto

* IAT = indirect antiglobulin test

Summary of Panel 1 and Panel 2

Probable antibodies: anti-C and anti-Jka

Note: Looking at the results of Panel 1 and 2 together, these two antibodies produce the best fit to explain the reaction patterns in both panels. This hypothesis needs to be confirmed by further testing (antibody exclusions).

Antibodies not ruled out: anti-K, anti-Fya, and anti-M

Self Test

  1. In the exclusion cell panel above, cells positive for C and Jka antigens have been set up. What is the rationale for setting up positive controls in selected cell panels?

    Answer

  2. Three cells have been tested to exclude the "not ruled out" antibodies. Decide which antibody that each cell is meant to exclude and then click on the question mark (?) buttons in the Comments column to test your choices.
Last modified on Monday, 10 October 2016 12:17